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Found 1091 clinical trials
Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging Study

This study intends to carry out a prospective, multi-center cohort study based on MRI to explore the incidence of structural and functional damage of central, brain and kidney in patiant with SSc and its clinical relevance, and to search for the characteristics of serological markers of structural and functional damage …

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 2 locations
Evaluation of Endoscopic Ultrasound Shear Wave Elastography (EUS-SWE) for the Diagnosis of Pancreatic Adenocarcinoma.

To assess the diagnostic accuracy of Shear Wave elastography (SWE) for the diagnosis of pancreatic adenocarcinoma.

adenocarcinoma
pancreatic adenocarcinoma
endoscopic ultrasound
  • 0 views
  • 07 Oct, 2021
  • 1 location
Characterization of the Platelet Inflammatory Response in NAFL and NASH

The primary objective of the study is to identify which features of platelet activation promote the inflammatory response that underlies the progression from NAFL to NASH. Therefore, the investigators plan: To characterize and compare the platelet inflammatory phenotype in NAFL vs NASH patients To study if and how the signaling …

  • 0 views
  • 22 Mar, 2022
  • 1 location
The Continuous Positive Airway Pressure Effect on Rho-associated Coiled-coil Containing Kinases Activity.

The ROCK (Rho-associated coiled-coil containing kinases) play a critical role in the pathogenesis of cardiovascular diseases and left ventricle hypertrophy (LVH). ROCK activity can be used as a clinical biomarker for the diagnosis and monitoring of cardiovascular disorders. Obstructive sleep apnea (OSA) increase cardiovascular disease and LVH. Continuous positive airway …

  • 0 views
  • 30 Sep, 2021
  • 1 location
Ultrasonographic Assessment of Painful and Stiff Hemiplegic Shoulder in Terms of Adhesive Capsulitis

Although a relationship has been reported between stroke and adhesive capsulitis, it is controversial whether the underlying cause of the capsular changes seen in hemiplegic shoulder pain is true adhesive capsulitis. Although there has been a limited number of studies, ultrasound, which has been reported as a sensitive and specific …

shoulder pain
capsulitis
Accepts healthy volunteers
  • 0 views
  • 16 Dec, 2021
  • 1 location
Long-term Characterization of Lipoprotein Apheresis Technologies for Individual Device Adaption (LOLIDA) (LOLIDA)

Lipoprotein apheresis is often applied as the final treatment of patient with severe and medication resistant dyslipidemia and progressive atherosclerosis. The high effectiveness of lipoprotein apheresis to improve the patient's metabolic situation and thereby strongly minimize the incidence of cardiovascular events was confirmed by a variety of studies. While in …

cholesterol measurement
atherosclerosis
dyslipidemia
hypercholesterolemia
  • 0 views
  • 21 Mar, 2022
Stem Cell Strategies for the Treatment of Chronic Asthma

The study is a pilot/laboratory study comparing the effects of MSC conditioned media on samples of airway cells in 3 participant groups with mild/moderate asthma (5 participants), severe asthma (5 participants), or no asthma (5 participants).

  • 0 views
  • 21 May, 2021
  • 1 location
Influence of Hormone Treatment in Radiation Therapy for Bladder Cancer

Bladder cancer is often treated with cystectomy or radiation therapy. Following radiation therapy patients will often have severe side effects from the treatment. Studies have suggested that simultanously treatment with androgen deprivation therapy during radiation therapy may be able to proctect stemcells in the bladder, thus improving tissue recovering post-radiation, …

hormone therapy
cancer
bladder cancer
androgen
bladder tumor
  • 0 views
  • 28 Feb, 2022
  • 1 location
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF

The purpose of this study is to examine small vessel disease (a condition in which the small arteries in the heart become narrowed). The investigators want to know how the small vessel disease contributes to pre-HFpEF (a condition with inadequate heart muscle function in the setting of preserved muscle pumping) …

  • 0 views
  • 27 Aug, 2021
  • 2 locations
Alterations of Gut Microbiota and Metabolites in ALD Patients

Alcohol-associated liver disease is one of the most prevalent liver diseases worldwide, and the leading cause of liver transplantation in the U.S. Alcohol-related liver disease is associated with changes in the intestinal microbiota and metabolites.

Accepts healthy volunteers
  • 0 views
  • 23 Jul, 2022
  • 1 location