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Found 1086 clinical trials
Technical Validation of MR Biomarkers of Obesity-Associated NAFLD (NAFLD)

The overall goal of this collaborative research program is to develop, validate and translate advanced quantitative magnetic resonance (MR) biomarkers of obesity-associated non-alcoholic fatty liver disease (NAFLD). This protocol represents the research plan for two distinct phases. The first phase is an optimization phase. The second phase is designed to …

Accepts healthy volunteers
MRI
magnetic resonance elastography
bariatric surgery
liver disease
  • 167 views
  • 28 Apr, 2022
  • 1 location
Electrophysiological Substrate in Patients With Barlow's Disease: Clinical Predictors of Arrhythmic Events and Impact of Mitral Surgery (MVP-A&S)

Mitral valve prolapse (MVP) is associated with malignant ventricular arrhythmias (VA) and sudden cardiac death. A proper electrophysiological and echocardiographic characterization of this population is missing. Moreover, the effects of mitral valve repair on the arrhythmic burden are still matter of debate. The investigators sought to explore the role of …

cardiac death
  • 0 views
  • 25 Oct, 2022
  • 1 location
Parametric Mapping in Paediatric Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is increasingly an important tool for diagnosis and management of cardiac diseases in children. One of the uses of MRI is tissue characterisation, in which the signal characteristics of the cardiac muscle (myocardium) can be determined with special techniques, known as parametric mapping. There is increasing …

Accepts healthy volunteers
heart disease
cardiac disorder
MRI
  • 0 views
  • 26 Feb, 2022
  • 1 location
Structural and Functional Impairment of Multiple Organs in Patients With Systemic Sclerosis: A MR Imaging Study

This study intends to carry out a prospective, multi-center cohort study based on MRI to explore the incidence of structural and functional damage of central, brain and kidney in patiant with SSc and its clinical relevance, and to search for the characteristics of serological markers of structural and functional damage …

Accepts healthy volunteers
  • 0 views
  • 26 Apr, 2022
  • 2 locations
Evaluation of Endoscopic Ultrasound Shear Wave Elastography (EUS-SWE) for the Diagnosis of Pancreatic Adenocarcinoma.

To assess the diagnostic accuracy of Shear Wave elastography (SWE) for the diagnosis of pancreatic adenocarcinoma.

pancreatic adenocarcinoma
adenocarcinoma
endoscopic ultrasound
  • 0 views
  • 07 Oct, 2021
  • 1 location
Characterization of the Platelet Inflammatory Response in NAFL and NASH

The primary objective of the study is to identify which features of platelet activation promote the inflammatory response that underlies the progression from NAFL to NASH. Therefore, the investigators plan: To characterize and compare the platelet inflammatory phenotype in NAFL vs NASH patients To study if and how the signaling …

  • 0 views
  • 22 Mar, 2022
  • 1 location
The Continuous Positive Airway Pressure Effect on Rho-associated Coiled-coil Containing Kinases Activity.

The ROCK (Rho-associated coiled-coil containing kinases) play a critical role in the pathogenesis of cardiovascular diseases and left ventricle hypertrophy (LVH). ROCK activity can be used as a clinical biomarker for the diagnosis and monitoring of cardiovascular disorders. Obstructive sleep apnea (OSA) increase cardiovascular disease and LVH. Continuous positive airway …

  • 0 views
  • 30 Sep, 2021
  • 1 location
Ultrasonographic Assessment of Painful and Stiff Hemiplegic Shoulder in Terms of Adhesive Capsulitis

Although a relationship has been reported between stroke and adhesive capsulitis, it is controversial whether the underlying cause of the capsular changes seen in hemiplegic shoulder pain is true adhesive capsulitis. Although there has been a limited number of studies, ultrasound, which has been reported as a sensitive and specific …

Accepts healthy volunteers
capsulitis
shoulder pain
  • 0 views
  • 16 Dec, 2021
  • 1 location
Long-term Characterization of Lipoprotein Apheresis Technologies for Individual Device Adaption (LOLIDA) (LOLIDA)

Lipoprotein apheresis is often applied as the final treatment of patient with severe and medication resistant dyslipidemia and progressive atherosclerosis. The high effectiveness of lipoprotein apheresis to improve the patient's metabolic situation and thereby strongly minimize the incidence of cardiovascular events was confirmed by a variety of studies. While in …

hypercholesterolemia
atherosclerosis
cholesterol measurement
dyslipidemia
  • 0 views
  • 21 Mar, 2022
Stem Cell Strategies for the Treatment of Chronic Asthma

The study is a pilot/laboratory study comparing the effects of MSC conditioned media on samples of airway cells in 3 participant groups with mild/moderate asthma (5 participants), severe asthma (5 participants), or no asthma (5 participants).

  • 0 views
  • 21 May, 2021
  • 1 location