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Found 57 clinical trials
Natural History of Craniofacial Anomalies and Developmental Growth Variants

Background Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics. Researchers want to learn more about these conditions by comparing people with face, head, and neck abnormalities to family members …

facial trauma
Accepts healthy volunteers
  • 21 Oct, 2022
  • 1 location
Study for Improving Maternal Pregnancy and Child Outcomes

outcomes, enabling future research on prevention and early detection for various adverse pregnancy outcomes which could be such as preterm birth and intrauterine growth restriction.

Accepts healthy volunteers
early pregnancy
fetal growth retardation
  • 17 Oct, 2021
  • 9 locations
Causes of Fetal Death: Comparison of Diagnostic Accuracy Between Extensive and Selective Protocol Testing

these two series, most deaths were related to placental diseases or fetal growth retardation. The hypothesis is that extensive protocol testing is not helpful in clinical practice and selective protocol

  • 25 Jan, 2021
  • 1 location
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) (PROMISSE)

The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can injure healthy organs can be used to predict poor pregnancy outcome in patients with systemic …

antiphospholipid syndrome
Accepts healthy volunteers
fetal death
  • 07 Oct, 2022
  • 4 locations
Molecular Screening Method for Preeclampsia (PREMOM)

Preeclampsia (PE) is a major obstetric complication with short- and long-term consequences for the mother and the fetus. Early screening tools to reduce its mortality and morbidity, as well as to prevent the life-threatening consequences are needed. Thus, the detection of women at risk of suffering PE is key to …

  • 06 Nov, 2021
  • 18 locations
First-trimester Placental Ultrasound Study (First PLUS)

An observational cohort study to assess the clinical utility of the OxNNet Toolkit for the prediction of adverse pregnancy outcomes.

  • 29 Apr, 2022
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally slow heart rate due to maternal antibody-mediated heart disease in the …

  • 22 Jun, 2021
  • 11 locations
Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies

Different screening modalities evaluation to develop algorithms to predict pregnancy complications in twin pregnancies, and evaluation of serologic response to BNT162b2 Pfeizer/BioNTech vaccination.

Accepts healthy volunteers
  • 20 Oct, 2021
  • 4 locations
Long-term Health After Severe Acute Malnutrition in Children and Adults: the Role of the Pancreas (SAMPA)

Whilst there is an increasing prevalence of overweight and obesity worldwide, malnutrition remains common. In addition, malnutrition, overweight, and infections often interact. The consequences of malnutrition after birth are little studied. Severe acute malnutrition in childhood remains common in Africa and Asia and many adult patients with tuberculosis or HIV, …

Accepts healthy volunteers
  • 14 May, 2022
  • 4 locations
The Registry Study of Takayasu Arteritis in East China

The Takayasu arteritis (TA) is a rare inflammatory large vessel arteritis which often occurs women in Aisa, one of which is China. The rare cases restricted the development of intervention strategy, especially in female patients who plan to be pregnant. So investigators try to recruit as many TA participants as …

systolic blood pressure
  • 17 Aug, 2021
  • 1 location