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Found 56 clinical trials
Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy (CHASAP)

A randomized clinical trial to assess the efficiency of acetylsalicylic acid (aspirin) 150 mg/day started before 20 weeks of gestation in the prevention on maternal and fœtal complications in pregnant women with chronic hypertension.

hypertension
aspirin
  • 0 views
  • 21 Apr, 2022
  • 10 locations
Active Pregnancy Against COVID-19 (ACPREGCOV)

Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence. During some phases of history, pregnancy has meant a period of seclusion for women (not only physical). One of the adverse consequences has been the common …

Accepts healthy volunteers
aerobic exercise
covid-19
prenatal
  • 0 views
  • 04 Oct, 2022
  • 1 location
HYDROxychloroquine in Syndrome Primary AntiPhospholipid (HYDROSAPL)

neonatal complications) related to APS. In the European APS register, maternal complications and IUGR were observed in 13% of cases, and prematurity in approximately 14% of cases despite treatment. In a

  • 7 views
  • 12 Mar, 2022
  • 1 location
Evolutionary Nutrition Pilot: Enhancing Fetal Growth and Brain Development

Globally, 250 million children do not reach their developmental potential and 155 million are stunted, yet few population-based studies have examined the direct effects of nutrient deficiencies on early brain development. This study will examine an evolutionary nutrition intervention during pregnancy derived from diets consumed for 99.9% of hominin history …

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development

This study is a randomized trial comparing 2 methods of human milk fortification for preterm infants in the neonatal intensive care unit (NICU). All participating infants will receive a human milk diet comprising maternal and/or donor milk plus multi-component and modular fortifiers. In one group (control), the milk will be …

prematurity
MRI
  • 0 views
  • 05 Jul, 2022
  • 1 location
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy (STORC)

This is a multicenter, single arm study of Sofosbuvir/Velpatasvir (SOF/VEL) for treatment of chronic hepatitis C infection during pregnancy. Treatment will be initiated during the second or third trimester in approximately 100 pregnant people. Maternal participants will take one SOF/VEL tablet once daily for 12 weeks (84 days) and followed …

  • 0 views
  • 06 May, 2022
  • 1 location
Continuous Glucose Monitoring and Cerebral Oxygenation in Preterm Infants

Neonatal hypoglicaemia is associated with impaired neurodevelopment outcomes in preterm infants. Thus, hypoglicemic events should be diagnosed and treated promptly. Unfortunately, hypo- and hyperglicaemia management is still controversial. The investigators aim to assess if a continuous glucose monitor (CGM) impacts on both short-term and long-term neurodevelopment. Primary outcome is the …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Investigating N-3 Fatty Acids to Prevent Neonatal Tobacco-related outcomeS

Smoking is the most important modifiable risk factor for adverse pregnancy outcomes including preterm birth, neonatal death, and maternal complications. Rates of smoking cessation during pregnancy are low, particularly in underserved populations, and currently approved pharmacotherapies for smoking cessation either are considered unsafe in pregnancy or have uncertain effectiveness. Identifying …

carbon monoxide
Accepts healthy volunteers
cotinine
smoking cessation therapy
nicotine product
  • 0 views
  • 08 Dec, 2021
  • 1 location
Prospective Randomized Study of the Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19

This research study is a randomized controlled trial in pediatric and young adult patients who have lost their sense of smell due to COVID-19 viral infection. The goals are: to learn more about the effects of smell retraining therapy on smell loss following COVID-19 and to determine if budesonide-saline irrigations …

  • 0 views
  • 27 Oct, 2022
  • 1 location
Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants. (SyncNIV)

Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns (gestational age at birth < 32 weeks) at their first approach to non invasive ventilation as first intention (soon after birth) or after extubation.

  • 0 views
  • 04 Oct, 2022
  • 1 location