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Found 284 clinical trials
Role of Probiotics in Treatment of Pediatric NAFLD Patients by Assessing With Fibroscan

The goal of this study is to evaluate the role of probiotics in the treatment of pediatric NAFLD by evaluating for steatosis and fibrosis with a Fibroscan machine. This will be done by performing a fibroscan during each visit and comparing patients' ALT at various intervals. This is an important …

  • 0 views
  • 28 Jan, 2021
  • 1 location
Non-Alcoholic Fatty Liver Disease the HEpatic Response to Oral Glucose and the Effect of Semaglutide (NAFLD HEROES)

Background In non-alcoholic fatty liver disease (NAFLD), fat accumulates in the liver and can cause damage. Researchers want to learn what causes the damage NAFLD

blood test
proton magnetic resonance spectroscopy
semaglutide
mri-pdff
steatosis
  • 22 views
  • 01 May, 2021
  • 1 location
Oltipraz for Liver Fat Reduction in Patients With Non-alcoholic Fatty Liver Disease Except for Liver Cirrhosis

Oltipraz inhibits fatty acid synthesis through AMPK-S6K1 pathway and LXRg-SREBP-1c pathway in liver.

fatty acids
fatty liver
cirrhosis
neutrophil count
liver disease
  • 5 views
  • 25 Jan, 2021
  • 15 locations
Liver Health and Metabolic Function in People With Obesity

This project aims to determine the effect of significant weight loss on rates on hepatic fibrogenesis in people with obesity.

bariatric surgery
body mass index
  • 53 views
  • 26 Jan, 2021
  • 1 location
Super HEROES: Searching How the Extract Rebaudioside Occludes Excess Steatosis

In order to determine whether rebaudioside consumption can be used as a treatment for adolescents with Non-alcoholic Fatty Liver Disease (NAFLD) by demonstrating a decrease in alanine

steatosis
liver disease
fatty liver
  • 1 views
  • 02 Feb, 2021
  • 1 location
Impact of Fructose on Metabolism Energy Homeostasis and MR Biomarkers in NAFLD

This study will advance several goals of the NIH Action Plan: 1) establish a multidisciplinary team to develop quantitative methodologies and imaging protocols for liver, 2) validate diagnostic criteria and methodologies for imaging in liver in both a cross-sectional and a longitudinal dietary intervention study of patients with NAFLD, 3) …

steatosis
fatty liver
fructose
liver injury
dietary modification
  • 9 views
  • 26 Jan, 2021
  • 1 location
Biological Adaptations of Strength Training.

A two-trial repeated measures design will be employed in this investigation. Both the control trial and the exercise trial will last for 3 months. During a week before the start of the study, participants will complete dietary recalls and record their habitual physical activity using accelerometers. Thereafter, body composition, ultrasound …

exercise intervention
diabetes
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study of Secukinumab Treatment in Patients With Plaque Psoriasis and Coexisting Non-alcoholic Fatty Liver Disease (NAFLD)

-steatotic (reduction of hepatic triglyceride content) and anti-fibrotic (reduction of hepatic fibrosis) effects of secukinumab in patients with psoriasis and coexisting non-alcoholic fatty liver disease

fibrosis
fatty liver
hepatic fibrosis
secukinumab
liver disease
  • 5 views
  • 11 May, 2021
  • 20 locations
Study of Various Treatments in Non-alcoholic Fatty Liver Disease (NAFLD) Patients Who Have Aspects of Non-alcoholic Steatohepatitis (NASH)

This study will look at how different single and combination study treatments will work in adults with non-alcoholic fatty liver disease (NAFLD) who have features of non-alcoholic

steatohepatitis
type 2 diabetes mellitus
hemoglobin a1c
fatty liver
diabetes
  • 0 views
  • 13 May, 2021
  • 16 locations
Unravelling Mechanisms of Fructose vs Glucose Consumption in the Pathogenesis and Progression of NAFLD

Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from simple fatty liver over steatohepatitis (NASH) to liver cirrhosis and cancer (HCC) and is a major and increasing

hemoglobin a1c
cirrhosis
fructose
diabetes
cancer
  • 1 views
  • 26 Jan, 2021
  • 1 location