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Found 22 clinical trials
Early Detection of GEnetic Risk (EDGE)

The study intervention involves having patients complete a familial cancer risk assessment survey. Those who are found to be at high risk will be offered genetic testing for a panel of

Accepts healthy volunteers
  • 16 views
  • 11 Mar, 2022
  • 2 locations
Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy

The purpose of this study is to evaluate the efficacy and safety of intramuscular (IM) administration of Engensis on pain in participants with painful diabetic peripheral neuropathy (DPN) in the feet and lower legs, as compared to Placebo, as a second Phase 3, well controlled study, sufficient in supporting the …

diabetes
hemoglobin a1c
gabapentin
peripheral neuropathy
diabetic peripheral neuropathy
  • 734 views
  • 30 Nov, 2021
  • 29 locations
  • 0 views
  • 23 May, 2022
  • 1 location
Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Background People with von Hippel-Lindau (VHL) can have problems with a variety of organs, such as the pancreas. The disease can cause tumors of the pancreas. This can result in life-threatening complications. Researchers want to learn more about these pancreatic tumors and how to better detect them. This may help …

pet/ct scan
cyst
neuroendocrine tumor
ct scan
dotatate
  • 0 views
  • 05 Jul, 2022
  • 1 location
Lay Coach-Led Early Palliative Care for Underserved Advanced Cancer Caregivers: The Project ENABLE Cornerstone RCT

Many of the 2.8 million family caregivers (FCGs) of persons with advanced cancer are underserved, particularly African-Americans and rural-dwellers in the Southern U.S.. Most have poor access and awareness of community-based palliative care services and have received no formal support or training despite providing assistance to their relatives an average …

Accepts healthy volunteers
  • 0 views
  • 14 Dec, 2021
  • 1 location
Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia

Background. Cancer is the leading cause of death by disease in children. Most pediatric tumors differ from adult tumors in terms of biological and clinical characteristics. In children, the part of genetic determinism could be higher since the role of environmental factors may be less pronounced than in adults and …

cancer
  • 0 views
  • 25 Mar, 2021
  • 1 location
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Background Allogeneic blood or marrow transplant is when stem cells are taken from one person s blood or bone marrow and given to another person. Researchers think this may help people with immune system problems. Objective To see if allogeneic blood or bone marrow transplant is safe and effective in …

cancer
urine tests
anesthesia
bone marrow transplant
lymphoma
  • 511 views
  • 30 Jun, 2022
  • 2 locations
Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Background Lymphoma is a type of blood cancer. Blood cell transplant can cure some people with lymphoma. Researchers want to see if they can limit the complications transplant can cause. Objective To test if a stem cell transplant can cure or control lymphoma. Also to test if new ways of …

cancer
hemolysis
urine tests
anaplastic large cell lymphoma
oxygen saturation
  • 15 views
  • 28 Jun, 2022
  • 2 locations
Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

Background Blood stem cells in the bone marrow make all the cells to normally defend a body against disease. Allogeneic blood or marrow transplant is when these stem cells are transferred from one person to another. Researchers think this treatment can provide a new, healthy immune system to correct T-cell …

shots
hemolysis
urine tests
ada2 deficiency
oxygen saturation
  • 138 views
  • 02 Jul, 2022
  • 2 locations
Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial Trial (CASCADE)

Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this randomized factorial trial is to identify components of a intervention (CASCADE) to enhance the decision support skills of family caregivers of persons with newly-diagnosed advanced cancer. Using a 2x2x2x2 full factorial design, 352 family caregivers of …

Accepts healthy volunteers
primary cancer
advanced cancer
  • 0 views
  • 16 Jun, 2022
  • 1 location