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Found 88 clinical trials
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Creation of a Prospective Cohort of Healthy and Sick Subjects and of a Collection of Associated Biological Resources for the Study of the Immune System and of Its Genetic and Environmental Determinants.

CoSImmGEn is a protocol set up to respond to the current lack of healthy and sick population cohorts. Biological resources from these cohorts allow researchers to study the immune system and its genetic and environmental determinants. Those cohorts and collections are open not only to the Pasteurian community but also …

  • 99 views
  • 15 Mar, 2021
  • 6 locations
None
BLI NBI or White Light Colonoscopy for Proximal Colonic Adenoma

This is a prospective randomised trial comparing the proximal adenoma detection rate and miss rate by blue laser imaging (BLI), narrow band imaging or white light colonoscopy.

narrow band imaging
  • 0 views
  • 08 Apr, 2021
  • 1 location
None
Autologous Platelet Concentrate (APC) in Intrabony Defects

The aim of this 12-month clinical study is to treat patients affected by gum disease (periodontitis) by a minor gum surgery that aims to reduce the depth of the gum pockets. In particular, the study will compare two types of gum surgery, one based on the use of a product …

  • 0 views
  • 04 Apr, 2021
  • 1 location
None
Cardiac Fibroblast Activation Detected by 68Ga-FAPI PET/MR

activated cardiac fibroblasts is the expression of FAP (fibroblast activation protein). A tracer (FAP inhibitor) for positron emission tomography that targets FAP has been used to measure relative FAP

  • 0 views
  • 22 Mar, 2021
  • 1 location
None
Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis

2 Year randomised, double-blind, placebo-controlled, parallel group study to determine the safety and efficacy of EPA-FFA gastro resistant capsules in FAP.

aspirin
rectal anastomosis
colectomy
eicosapentaenoic acid
  • 1 views
  • 26 Jul, 2021
  • 29 locations
None
The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots

), factor VIIIc, activated partial thromboplastin time (aPTT) and activated partial thromboplastin time plus activated protein C (aPTT + APC). Both groups will undergo a GYN exam with screening

protein c
copper
d-dimer
levonorgestrel
thrombosis
  • 148 views
  • 07 Nov, 2020
  • 1 location
None
Impaired Immunity in Patients With Cancer: Influence of Cancer Stage Chemotherapy and Cytomegalovirus Infection

cells (DCs), the most potent APC, are located at sites of pathogen entry, acquire antigens from pathogens or pathogen-infected cells, and process these antigens for both class I and class II

solid tumor
  • 6 views
  • 07 Nov, 2020
  • 1 location
None
A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis

The purpose of this study is to determine the effect of JNJ-64251330 in participants with Familial Adenomatous Polyposis (FAP) on colorectal polyp burden (sum of the polyp diameters).

  • 0 views
  • 08 Dec, 2021
  • 23 locations
None
Efficacy of an Internet-based Intervention for Dental Anxiety

The overall objective of the activities described in this protocol is to examine the efficacy of the Internet-based intervention in the reduction of dental anxiety in patients seeking dental treatment. This study has 2 primary objectives and 2 secondary objectives: Primary Objective 1-Therapy Aides: To compare the efficacy of the …

  • 0 views
  • 22 Aug, 2021
  • 1 location
None
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction Vascular Oxidative Stress in African Americans

Specific Aim 1: To test the hypothesis that prolonged (3-month) treatment with galantamine inhibits NADPH IsoLG-protein adducts formation and improves markers of endothelial cell (EC) dysfunction in AAs. Aim 1a: The investigators will determine if galantamine inhibits NADPH IsoLG-protein adducts formation, superoxide production, and immune cell activation compared to placebo. …

Accepts healthy volunteers
  • 0 views
  • 07 Dec, 2021
  • 1 location