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Found 49 clinical trials
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer

external beam radiation therapy (EBRT) treatments lead to less side effects. This study is also looking at patient outcomes, quality of life, and overall survival for patients receiving this treatment.

external beam radiation therapy
androgen suppression
antiandrogen therapy
androgens
cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location
MRI Guided Transurethral HIFU for Various Prostate Diseases

patients to each group with criteria as follows: localised prostate cancer (PC); locally advanced PC; locally recurrent PC after external beam radiation therapy (EBRT); benign prostatic hyperplasia (BPH

benign prostatic hypertrophy
bladder outlet obstruction
cystoscopy
prostatectomy
transrectal ultrasound
  • 55 views
  • 16 May, 2021
  • 1 location
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients

cancer patients. This phase III clinical trial is designed to compare the safety of a standard pelvic external beam radiation therapy (EBRT) combined with a high dose rate brachytherapy (HDRB

external beam radiation therapy
endocrine therapy
ct scan
neutrophil count
androgen suppression
  • 224 views
  • 27 Sep, 2021
  • 13 locations
Comparing Supplemental Topical Agents for the Treatment of Acute Radiation Dermatitis in Patients With Breast Cancer

external beam radiation therapy (EBRT). However, it is not known whether one is better than the other in treating or preventing radiation dermatitis.

lumpectomy
cancer
breast cancer
invasive breast cancer
carcinoma in situ
  • 0 views
  • 04 Oct, 2022
  • 1 location
Multiparametric MRI for Assessing Radiotherapy Treatment Response of Prostate Cancer (NA_00067284)

Prostate cancer is one of most common cancers in America, affecting 1 in 6 men. External beam radiation therapy is one of the common methods to treat prostate cancer. Although radiotherapy is

external beam radiation therapy
  • 10 views
  • 25 Oct, 2022
  • 1 location
Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer

The purpose of this study is to evaluate the dose of High Dose Rate (HDR) brachytherapy chosen for this study as well as a commonly used alternate form of brachytherapy called low dose rate (or seed) brachytherapy. Investigators would like to understand how these treatments control the prostate cancer and …

biopsy of prostate
transrectal ultrasound
brachytherapy
ct scan
adenocarcinoma of prostate
  • 16 views
  • 07 Oct, 2022
  • 7 locations
Phase II Study of Pembrolizumab (MK-3475) in Combination With Standard Therapy for Newly Diagnosed Glioblastoma

This phase II trial studies the side effects and how well pembrolizumab works in combination with standard therapy in treating patients with glioblastoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

MRI
erythropoietin
direct bilirubin
tumor cells
serum pregnancy test
  • 72 views
  • 17 Oct, 2022
  • 1 location
A Phase I Clinical Trial of Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help. Objective To learn the highest dose of selinexor that people with brain cancer can tolerate when given …

MRI
temozolomide
glioblastoma multiforme
malignant brain tumor
ct scan
  • 47 views
  • 23 Oct, 2022
  • 1 location
PROTECT: On-line Adaptive Proton Therapy for Cervical Cancer (PROTECT)

This prospective, multicenter, nonrandomized phase-II-trial investigates in clinical practice the differences between intensity modulated proton therapy (IMPT) and standard intensity-modulated radiation therapy (IMRT) or volumetric-modulated arc therapy (VMAT) in the effects on dose-volume parameters and treatment-related morbidity for women with locally advanced cervical cancer undergoing chemoradiation.

adenocarcinoma
metastasis
treatment regimen
brachytherapy
carcinoma
  • 0 views
  • 16 Jun, 2022
  • 1 location
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is …

lumpectomy
breast cancer
partial breast irradiation
sentinel node
carcinoma in situ
  • 27 views
  • 03 Nov, 2021
  • 8 locations