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Found 49 clinical trials
In Vivo Succinate Detection After External Beam Radiation Therapy in SDHx- Paragangliomas

Qualitative and quantitative biomarker of response to radiotherapy is needed in paragangliomas. We aim at assessing the added value of 1H-SRM for the evaluation of early response to EBR therapy in patients with cervical SDHx PGL.

  • 0 views
  • 31 Dec, 2021
  • 3 locations
Lutathera for the Treatment of Inoperable, Progressive Meningioma After External Beam Radiation Therapy

(progressive) after external beam radiation therapy. Lutathera is a radioactive drug administered in the vein that is designed to target and kill cancer cells. The goal of this study is to determine whether

  • 5 views
  • 24 May, 2022
  • 1 location
Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

This phase II trial studies how well pembrolizumab and external beam radiation therapy work in treating patients with non-Hodgkin lymphoma that has come back (relapsed) or does not respond to

tumor cells
cancer
t-cell lymphoma
hodgkin's disease
pembrolizumab
  • 8 views
  • 29 May, 2021
  • 2 locations
Nelfinavir Cisplatin and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery

This phase I trial studies the side effects and best dose of nelfinavir when given together with cisplatin and external beam radiation therapy in treating patients with vulvar cancer that has

  • 0 views
  • 25 Jan, 2021
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

This early phase I trial studies the side effects of autologous dendritic cells and a vaccine called Prevnar in treating patients with liver cancer that cannot be removed by surgery after undergoing standard high-dose external beam radiotherapy. Autologous dendritic cells are immune cells generated from patients' own white blood cells …

tumor cells
cancer
platelet count
computed tomography
liver cancer
  • 6 views
  • 14 Jun, 2022
  • 1 location
Pilot Study of Resection and GammaTile Followed by Concomitant External Beam Radiation Therapy (EBRT) and Temozolomide (TMZ) and Adjuvant in Newly Diagnosed Glioblastoma (GBM) (GESTALT)

In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local control or prolonged overall survival. As discussed above it seems unlikely that patient outcomes will be significantly improved with radiation dose escalation given at the time of the EBRT boost. However, …

  • 0 views
  • 14 Oct, 2022
  • 1 location
Hypo-Combi Trial: Hypofractionated EBRT Plus HDR-BT Boost for Prostate Cancer

Hypo-Combi Trial: A Prospective Phase I/II Study of Combined Hypofractionated External Beam Radiation Therapy (EBRT) plus Interstitial High-Dose-Rate Brachytherapy (HDR-BT) for Intermediate/High

  • 0 views
  • 23 Aug, 2021
  • 1 location
CivaSheet With Radical Prostatectomy & Adjuvant External Beam Radiation

A phase I single-arm open label dose escalation study to evaluate the maximum tolerated dose (MTD) and safety of Civasheet® with radical prostatectomy (RP) and adjuvant external beam radiation

prostatectomy
adenocarcinoma of prostate
adenocarcinoma
immunological adjuvant
extracapsular extension
  • 8 views
  • 13 Feb, 2022
  • 2 locations
A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer

The purpose of this study is to find out whether combining a shorter than standard course of ADT with standard prostate brachytherapy and hypofractionated external beam radiation therapy is a

  • 0 views
  • 04 Oct, 2022
  • 7 locations
Salvage Cryotherapy for Recurrent Prostate Cancer After Radiation Therapy

prostate (SCAP). Our study hypothesis is that SCAP constitutes an effective and safe approach to treat local prostate cancer recurrence after brachytherapy or external beam radiation therapy (EBRT

  • 0 views
  • 25 May, 2021
  • 2 locations