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Found 67 clinical trials
Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy

an effective and safe alternative to the commonly-used standard 3D-conformal external beam radiotherapy, spares more normal breast and lung tissue, and may lead to improved clinical outcomes.

lumpectomy
magnetic resonance imaging of breast
partial breast irradiation
breast cancer staging
mammogram
  • 7 views
  • 08 Nov, 2020
  • 1 location
Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years (HAI-5-III)

This study will evaluate the effect of highly accelerated external beam radiotherapy (EBRT) in 5 fractions over 10 days compared to 15 fractions over 3 weeks for early as well as locally

  • 4 views
  • 25 Feb, 2022
  • 1 location
Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix (ARTIA-Cervix)

of external beam radiotherapy (EBRT) and will use the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).

  • 0 views
  • 19 Jun, 2022
  • 2 locations
Partial Prostate Salvage High Dose Rate Brachytherapy (SalvageHDR)

A dose-response relationship for radiation in the management of prostate cancer is well established. Local recurrence of prostate cancer after external beam radiotherapy occurs in at least 40

antiandrogen therapy
platelet count
brachytherapy
external beam radiation therapy
bone scan
  • 4 views
  • 25 Feb, 2022
  • 1 location
Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer

The goal of this study is to evaluate combined radioactive iodine (RAI, 131-I) and external beam radiotherapy (XRT) to optimize the radiation dose delivered to treat well differentiated thyroid

  • 0 views
  • 09 Jun, 2022
  • 1 location
High-Dose-Rate Brachytherapy

locally advanced prostate cancer will receive a boost of prostate-targeted HDR brachytherapy during external beam radiotherapy. This technique will be prospectively evaluated in up to 100 patients

  • 12 views
  • 24 Jan, 2022
  • 1 location
PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer (PORTEC-4a)

and molecular risk profile to determine if participants should receive no adjuvant therapy, vaginal brachytherapy or external beam radiotherapy based on a favourable, intermediate or unfavourable

  • 77 views
  • 01 Mar, 2022
  • 30 locations
PROfiling Based Endometrial Cancer Adjuvant Therapy (PROBEAT)

integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular

  • 0 views
  • 10 May, 2022
  • 1 location
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features: the p53abn-RED Trial, the MMRd-GREEN Trial, the NSMP-ORANGE Trial and the POLEmut-BLUE Trial (RAINBO)

The RAINBO umbrella program consists of four clinical trials investigating new adjuvant therapies in endometrial cancer patients. Eligible patients will be assigned to one of the four RAINBO trials based on the molecular profile of their cancer: p53 abnormal endometrial cancer patients to the p53abn-RED trial mismatch repair deficient endometrial …

cancer
carboplatin
megestrol
paclitaxel
durvalumab
  • 0 views
  • 19 Sep, 2022
  • 2 locations
Image Based Brachytherapy in Locally Advanced Cervical Cancers - a Randomized Controlled Trial (COMBAT-Cx)

Purpose of the study is to determine whether Image based brachytherapy is superior in terms of local control to Conventional radiograph based brachytherapy in locally advanced cervical cancers in a Phase III randomized setting.

adenocarcinoma
cervical disease
squamous cell carcinoma
cancer
carcinoma
  • 43 views
  • 24 Feb, 2022
  • 1 location