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Found 65 clinical trials
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A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 196 views
  • 08 Nov, 2020
  • 1 location
MRI Screening of Second Primary Cancer Occurring Within Radiation Fields After Treatment by External Beam Radiation Therapy for Hereditary Retinoblastoma (DepiSCARRH)

treated by external beam radiation therapy (EBRT).

beam radiation
second primary cancer
bilateral retinoblastoma
cancer
  • 28 views
  • 27 Jan, 2021
  • 1 location
Targeted Therapy and Avelumab in Merkel Cell Carcinoma

type of peptide receptor radionuclide therapy; PRRT) or external beam radiation therapy (EBRT) in patients with metastatic Merkel cell carcinoma (mMCC).

  • 0 views
  • 03 Mar, 2021
  • 6 locations
A Trial Comparing Acute Toxicity in Patients With Gynecological Cancer Treated With VMAT

This is a randomized, controlled, open-label, prospective and longitudinal clinical trial. Rectal, intestinal and bladder EBRT-related toxicity will be assessed according to RTOG / EORTC scales at the first day of EBRT, during the 2nd, 3rd and 4th week of treatment, and 1, 3 and 6 months after the end …

cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer

The mechanisms responsible for the development of hormonal refractory prostate cancer (HRPC) have been elusive. Genetic inactivation/loss of the PTEN tumor suppressor gene occurs in 30-60% of advanced prostate cancers and in 20% of the localized form. Researchers hypothesize that PTEN loss is a landmark genetic event in prostate cancer …

castration-resistant prostate cancer
tumor progression
PTEN
adenocarcinoma of prostate
adenocarcinoma
  • 3 views
  • 07 Nov, 2020
  • 1 location
Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

The primary objective of this protocol is to evaluate the response rate of bilateral disease participants who have at least one eye with advanced intra-ocular retinoblastoma (stratum B) using upfront therapy with chemotherapy delivered directly to the eye. The main biology objective is to improve our understanding of the biology …

intraocular retinoblastoma
topotecan
nervous
unilateral retinoblastoma
renal function
  • 43 views
  • 04 Feb, 2021
  • 1 location
Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer

This is an open label, prospective, trial that begins with a phase Ib safety run-in followed by a phase II expansion cohort.

nivolumab
testosterone
platelet count
gilbert's syndrome
metastasis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Targeted Microwave Focal Therapy

Focal therapy (FT) for prostate cancer (PCa) is an interesting therapeutic option for localized disease with a favorable low- to intermediate-risk profile. The aim of this approach is to offer a personalized and less aggressive treatment as compared to radical treatments such as radical prostatectomy (RP) or primary radiation therapy, …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Pelvic RT Versus Prophylactic Extended-field RT in Patients With Cervical Cancer

in selected patients with cervical cancer treated with definitive concurrent chemoradiotherapy. External beam radiation therapy is delivered with intensity-modulated radiation therapy (IMRT).

adenosquamous carcinoma
pet/ct scan
pet/ct
paclitaxel
chemoradiotherapy
  • 1 views
  • 23 Jan, 2021
  • 2 locations
Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer

The primary objective of the trial is to assess if GnRH antagonists in combination with external beam radiation therapy improve progression free survival (progression that can be biological

androgen suppression
degarelix
testosterone
gonadorelin
immunological adjuvant
  • 135 views
  • 23 Jan, 2021
  • 42 locations