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Found 51 clinical trials
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A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 229 views
  • 25 Mar, 2021
  • 1 location
  • 28 views
  • 24 Feb, 2022
  • 1 location
A Phase Ib/II Study of Combination Avelumab With Peptide Receptor Radionuclide Therapy or Conventional Fractionated Radiotherapy in Patients With Metastatic Merkel Cell Carcinoma (GoTHAM)

type of peptide receptor radionuclide therapy; PRRT) or external beam radiation therapy (EBRT) in patients with metastatic Merkel cell carcinoma (mMCC).

  • 0 views
  • 16 Sep, 2022
  • 6 locations
Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

The primary objective of this protocol is to evaluate the response rate of bilateral disease participants who have at least one eye with advanced intra-ocular retinoblastoma (stratum B) using upfront therapy with chemotherapy delivered directly to the eye. The main biology objective is to improve our understanding of the biology …

etoposide
renal function
nervous
cyclophosphamide
filgrastim
  • 43 views
  • 15 Sep, 2022
  • 1 location
Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer (Rad2Nivo)

This is an open label, prospective, trial that begins with a phase Ib safety run-in followed by a phase II expansion cohort.

adenocarcinoma
gilbert's syndrome
bone metastases
platelet count
nivolumab
  • 0 views
  • 03 May, 2022
  • 1 location
Targeted Microwave Focal Therapy

Focal therapy (FT) for prostate cancer (PCa) is an interesting therapeutic option for localized disease with a favorable low- to intermediate-risk profile. The aim of this approach is to offer a personalized and less aggressive treatment as compared to radical treatments such as radical prostatectomy (RP) or primary radiation therapy, …

  • 4 views
  • 09 Mar, 2022
  • 1 location
Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer

The primary objective of the trial is to assess if GnRH antagonists in combination with external beam radiation therapy improve progression free survival (progression that can be biological

external beam radiation therapy
luteinizing hormone-releasing hormone agonist
ct scan
adenocarcinoma
adenocarcinoma of prostate
  • 135 views
  • 12 Sep, 2021
  • 42 locations
Pelvic RT Versus Prophylactic Extended-field RT in Patients With Cervical Cancer

in selected patients with cervical cancer treated with definitive concurrent chemoradiotherapy. External beam radiation therapy is delivered with intensity-modulated radiation therapy (IMRT).

cancer
external beam radiation therapy
chemoradiotherapy
pet/ct
adenocarcinoma
  • 17 views
  • 12 Mar, 2022
  • 2 locations
PSMA-PET Guided Hypofractionated Salvage Prostate Bed Radiotherapy (PERYTON)

After radical prostatectomy approximately 15-40% of men develop a biochemical recurrence (BR) within 5 years. The standard treatment of post-prostatectomy BR is salvage external beam

  • 0 views
  • 23 Apr, 2022
  • 7 locations
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Using PET/CT Imaging

This phase III trial compares the addition of apalutamide, with or without targeted radiation therapy, to standard of care treatment versus standard of care treatment alone in patients with prostate cancer biochemical recurrence (a rise in the blood level of prostate-specific antigen [PSA] after treatment with surgery or radiation). Diagnostic …

cancer
definitive treatment
ct scan
goserelin
leuprolide
  • 0 views
  • 27 May, 2022
  • 21 locations