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Found 67 clinical trials
Featured trial
Seclidemstat in the treatment of Ewing sarcoma and other select sarcomas

If you are eligible and agree to participate, you will receive the investigational (called "study") medication. Whether you receive the study medication alone or with another type of 'standard of care' treatment will depend on your type of sarcoma. The study doctor/staff will talk with you more about this.You will …

  • 0 views
  • 04 Feb, 2022
  • 16 locations
Featured trial
AEWS07B1: Collecting and Storing Biological Samples From Patients with Ewing Sarcoma

AEWS07B1: Collecting and Storing Biological Samples From Patients with Ewing Sarcoma

  • 60 views
  • 08 Nov, 2020
  • 1 location
Featured trial
AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 380 views
  • 08 Nov, 2020
  • 1 location
Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence

To assess the neurocognitive outcomes in patients treated with chemotherapy for a malignant bone tumor during childhood and adolescence and the factors associated with neurocognitive impairment and/or complaints

  • 0 views
  • 15 Oct, 2021
  • 1 location
Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 16 views
  • 14 May, 2022
  • 20 locations
Irinotecan and Temozolomide for Ewing Sarcoma

The investigators explored the activity of vincristine and irinotecan combined with temozolomide (VIT) in patients with relapsed and metastatic Ewing Sarcoma.

ifosfamide
cyclophosphamide
temozolomide
immunosuppressive
treatment consisted of
  • 55 views
  • 28 Feb, 2022
  • 1 location
SARC037: A Phase I Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients

This study evaluates the trabectedin and irinotecan in the treatment of Ewings sarcoma, with a EWS-FLI1 mutation. Patients will also receive an infusion of 18F-FLT in combination with a Positron

refractory ewing sarcoma
measurable disease
irinotecan
  • 0 views
  • 12 May, 2021
  • 4 locations
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer (PIVOT IO 020)

The purpose of this study is to first, in Part A, assess the safety, tolerability and drug levels of Bempegaldesleukin (BEMPEG) in combination with nivolumab and then, in Part B, to estimate the preliminary efficacy in children, adolescents and young adults with recurrent or treatment-resistant cancer.

central nervous system tumor
nervous
lymphoma
cancer
  • 0 views
  • 26 Mar, 2022
  • 7 locations
A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.

non-metastatic invasive breast carcinoma, high-grade soft tissue sarcoma, osteosarcoma, Ewing's sarcoma, acute myeloid leukemia, Hodgkin's or aggressive non-Hodgkin's lymphoma. Four assessment visits

  • 0 views
  • 16 Feb, 2021
  • 1 location
Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) (MICCHADO)

Methodology Prospective, multicentric, open, non-randomised, non-therapeutic, interventional study

ewing's sarcoma
childhood cancer
brain tumor
kidney tumors
bone marrow procedure
  • 30 views
  • 16 Mar, 2022
  • 13 locations