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Found 74 clinical trials
Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial)

This study is designed to determine the safety and efficacy of two calcineurin inhibitor free treatment groups 1) a belatacept, everolimus and early corticosteroid withdrawal (ECSWD

  • 3 views
  • 01 May, 2021
  • 2 locations
Efficacy and Safety of Everolimus Versus Mycophenolate Mofetil in Liver Transplant Recipients.

The purpose of this study is to evaluate the efficacy and safety of CertiroBell tablet compared with mycophenolate mofetil in primary living donor liver transplant recipients.

blood concentration
everolimus
living donor liver transplant
mycophenolate
  • 0 views
  • 24 Jan, 2021
Phase I Trial of VS-6766 Alone and in Combination With Everolimus (RAF/MEK)

IIB). Up to 44 patients with solid tumours containing BRAF, KRAS and/or NRAS mutations will take VS-6766 in combination with everolimus (Part IID). Of these, 20 patients will comprise the Part

BRAF
cancer
KRAS
bone marrow procedure
NRAS
  • 31 views
  • 12 May, 2022
  • 2 locations
A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients

collecting, expanding and infusing a specific certain type of immune cell known as Regulatory T cells (Treg cells) to renal transplant recipients who are using Zortress (Everolimus) as immunosuppressive

solitary kidney
nephropathy
kidney transplant
immunosuppression
immunosuppressive agents
  • 1 views
  • 23 May, 2022
  • 1 location
A Phase 0 /II Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

In the proposed trial, patients will be administered ribociclib+everolimus prior to surgical resection of their tumor. Recurrent GBM patients will be randomized into one of the three time

neutrophil count
PTEN
malignant glioma
EGFR
recurrent malignant glioma
  • 7 views
  • 19 Feb, 2022
  • 3 locations
Trametinib and Everolimus for the Treatment of Pediatric and Young Adult Patients With Recurrent Low Grade Gliomas (PNOC021)

This phase I trial studies the side effects and best dose of trametinib and everolimus in treating pediatric and young adult patients with low grade gliomas that has come back (recurrent

  • 0 views
  • 28 May, 2022
  • 12 locations
A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma

This phase II trial studies how well everolimus and letrozole with or without ribociclib work in treating participants with endometrial cancer that has spread to other areas of the body or has

cancer
liver metastasis
gilbert's syndrome
letrozole
EGFR
  • 80 views
  • 27 Jan, 2022
  • 2 locations
Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

This phase II trial compares the effects of lenvatinib given in combination with everolimus to the effects of cabozantinib given alone in treating patients with renal cell cancer (RCC) that has

  • 0 views
  • 25 Mar, 2022
  • 1 location
Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

This phase I trial studies the side effects and best dose of ceritinib and everolimus in treating patients with solid tumors that have spread from where they started to nearby tissue or lymph

neutrophil count
cancer
lung cancer
liver metastasis
ROS1
  • 193 views
  • 24 Jan, 2022
  • 1 location
Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

This phase I trial studies the side effects and best dose of neratinib in combination with everolimus, palbociclib, or trametinib in participants with solid tumors with EGFR mutation

liver metastasis
somatic mutation
growth factor
EGFR
KRAS
  • 36 views
  • 31 Jan, 2022
  • 1 location