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Found 6 clinical trials
Single-dose Anti-CD20 Antibody With Bortezomib for Relapsed Refractory Autoimmune Hemolytic Anemia

Patients of relapsed and refractory warm autoimmune hemolytic anemia or EVANS syndrome aged 18 to 80 will be included in this study. The treatment regimen is a single dose anti-CD20 antibody

treatment regimen
prednisone
  • 8 views
  • 21 Oct, 2021
  • 1 location
Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, single-center, one-arm clinical trial aims at evaluating the efficacy and safety of avatrombopag in Chinese adult Immune Thrombocytopenia (ITP) patients with autoantibodies fail (due to intolerance or resistance) to eltrombopag or herombopag treatment.

eltrombopag
arthritis
thrombopoietin receptor agonists
immune globulin
sjogren's syndrome
  • 0 views
  • 12 Aug, 2021
  • 1 location
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapy(BAT)in adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

rituximab
arthritis
igiv
azathioprine
immune tolerance
  • 0 views
  • 26 May, 2022
  • 1 location
Sirolimus Treatment for Newly Diagnosed Primary Acquired PRCA

Pure red cell aplasia (PRCA) is a kind of anemia characterized by severe reticulocytopenia and obvious bone marrow erythroblastic cells decreased. Cyclosporine A and /or steroids are the first line therapy but some patients were refractory or intolerance to the treatment. The effects of the second line therapy are also …

  • 0 views
  • 17 Jul, 2021
  • 1 location
The Safety of Repurposing Daratumumab for Relapsed or Refractory Autoimmune Antibody Mediated Hemolytic Anemia (DARA-AIHA)

A single-arm study utilizing a 6 x 4 expansion design using daratumumab SC treatment for patients with refractory Autoimmune Hemolytic Anemia.

  • 0 views
  • 02 Jul, 2022
  • 1 location
Severe Immune Cytopenia Registry Www.Sic-reg.Org (sic-reg)

Prospective registry study for children and young adults with severe immune cytopenias (persisting/chronic immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome) to improve

cytopenia
autoimmune thrombocytopenia
evans syndrome
autoimmune hemolytic anemia
thrombocytopenia
  • 5 views
  • 04 Mar, 2022
  • 1 location