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Found 325 clinical trials
Prognostic Evaluation of Changing Endocrine Therapy in Women With Breast Cancer

It suggests in the Guideline that the postmenopausal women with breast cancer who have taken selective estrogen receptor modulators (SERMs) therapy for 2-3 years could benefit from changing

metastasis
endocrine therapy
aromatase inhibitor
estrogen
x-rays
  • 0 views
  • 21 Jan, 2021
MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)

The purpose of this study is to evaluate the efficacy of addition of letrozole to the standard maintenance therapy in subjects following a primary diagnosis of Estrogen-receptor (ER) positive

platinum-based chemotherapy
ovarian epithelial carcinoma
letrozole
cancer chemotherapy
cancer of the ovary
  • 0 views
  • 02 Jul, 2021
  • 20 locations
To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

This is a phase II open-label, multicentre, randomized trial. The study assesses the treatment of postmenopausal patients with hormone receptor positive/HER2 positive early breast cancer with neoadjuvant palbociclib in combination with hormonal therapy and HER2 blockade, versus the treatment with paclitaxel in combination with HER2 blockade.

breast cancer
her2/neu-positive breast cancer
muga scan
estrogen
estradiol
  • 17 views
  • 11 May, 2021
  • 63 locations
Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)

, to secrete the reproductive hormones that influence sex hormone (testosterone, estrogen) levels and gamete (sperm, egg cell) production. This study involves a detailed evaluation and 24-48

testosterone
estrogen
estradiol
idiopathic hypogonadotropic hypogonadism
gonadotropin
  • 85 views
  • 27 Jan, 2021
  • 1 location
Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer

-positive / HER2-negative breast cancer which has spread beyond the original tumor and/or to other organs. During this study, anti-hormone therapy will consist of either a selective estrogen receptor

HER2
aromatase inhibitor
endocrine therapy
estrogen
letrozole
  • 0 views
  • 24 May, 2021
  • 69 locations
Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer

duration of response in the 2 treatment arms To evaluate the PFS according to the estrogen receptor 1 gene (ESR1) mutation status in the 2 treatment arms To evaluate the pharmacokinetics

breast cancer
adenocarcinoma
estrogen
advanced breast cancer
estrogen receptor
  • 213 views
  • 13 Jun, 2021
  • 169 locations
Prostate Adenocarcinoma TransCutaneous Hormones

investigation of the treatment in this setting, as recommended by the IDMC.. PURPOSE: This randomized phase III trial is studying how well the estrogen skin patch works compared with luteinizing hormone

adenocarcinoma
testosterone
diabetes
estrogen
estradiol
  • 291 views
  • 27 Jan, 2021
  • 2 locations
POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer

surgery (BCS) or mastectomy, Estrogen receptor (ER) status (positive, negative), Number of positive nodes (1, 2), Intra-operative sentinel assessment using OSNA (yes, no). Interventions The study

breast-conserving surgery
estrogen
erbb2
growth factor
estrogen receptor
  • 1778 views
  • 04 Jul, 2021
  • 50 locations
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …

  • 139 views
  • 19 May, 2021
  • 482 locations
Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

This randomized clinical trial studies how well online genetics educational video with or without pre- and/or post-telephone genetics counseling works in assessing cancer-risk distress in patients with triple negative breast cancer. Online genetic education and telephone genetic counseling may help the doctors learn the stress a person feels about their …

breast cancer
estrogen
genetic testing
palb2
genetic counseling
  • 24 views
  • 23 Jan, 2021
  • 5 locations