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Found 7 clinical trials
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A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the Treatment of Subjects With Moderate-to-Severe Primary Restless Legs Syndrome (RLS)

A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, Parallel-Group Study to Compare the Efficacy, Tolerability, and Safety of 3 Doses of Gabapentin Enacarbil (GSK1838262) With Placebo in the Treatment of Subjects With Moderate-to-Severe Primary Restless Legs Syndrome (RLS)

  • 584 views
  • 08 Nov, 2020
  • 1 location
Cyclosporine A Pretreatment and Kidney Graft Function

Organ donors included in the study are randomized to a control group or an intervention group receiving 2.5 mg/kg of cyclosporine A before organ procurement. Harvested kidneys from these patients are transplanted to chronic kidney insufficiency patients. According to the pretreatment of the transplant, delayed graft function during the first …

chronic renal insufficiency
cyclosporine
delayed graft function
  • 18 views
  • 24 Jan, 2021
  • 1 location
Dose Individualization of Pemetrexed - IMPROVE-I

with an estimated creatinine clearance <45ml/min that meet all other requirements for pemetrexed treatment. Intervention:Patients will be treated with pemetrexed, with dosing based on renal

folic acid
folate antagonist
antifolate
renal function
pemetrexed
  • 4 views
  • 23 Sep, 2021
  • 5 locations
Fibrosis in Renal Allografts

This prospective, randomized study, comparing sirolimus to cyclosporine in renal transplant recipients, has two major objectives: 1. -To determine the incidence and the degree of interstitialfibrosis and arteriosclerosis, as wel as the glomerular volume in protocol biopsies at 6 months in sirolimus-and in cyclosporine-treated renal allograft recipients, by means of …

sirolimus
kidney transplant
cyclosporine
daclizumab
  • 40 views
  • 07 Nov, 2020
  • 3 locations
Study of Baricitinib a JAK1/2 Inhibitor in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Background Chronic graft versus host disease (cGVHD) can affect people who had a hematopoietic stem cell transplant using donor cells. It is often fatal. It is usually treated with high doses of steroids. But that helps only about half the people in the long term. Researchers want to see if …

cell transplantation
second-line therapy
urine test
cancer
systemic therapy
  • 23 views
  • 24 Sep, 2021
  • 1 location
HIV Pre-exposure Prophylaxis Implementation Study in South Korea

The primary objective of this study is to examine acceptability, patterns of use, rates of adherence, safety , and measured levels of drug when high risk men who have sex with men (MSM) are provided open-label tenofovir/emtricitabine (TDF/FTC) for PrEP in South Korea. Secondary objectives are 1) to evaluate HIV …

HIV Vaccine
immune globulin
tenofovir
pre-exposure prophylaxis (prep)
emtricitabine
  • 0 views
  • 26 Jan, 2021
Lixiana Acute Stroke Evaluation Registry

Study Design: Lixiana Acute Stroke Evaluation Registry (LASER) is a randomized controlled trial with an associated registry. Patients with previously known or newly diagnosed atrial fibrillation (AF) and acute ischemic stroke within five days will be randomized 2:1 to early ( 5 days) or delayed (6-14 days) edoxaban initiation. Ischemic …

edoxaban
apixaban
transient ischemic attack
ct scan
holter monitor
  • 1 views
  • 24 Mar, 2021
  • 1 location