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Found 1822 clinical trials
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ALN-CC5-005: A Phase 2, Randomized, Double-blind, Placebo-controlled Study of Cemdisiran in Adult Patients with IgA Nephropathy

This is a multicenter, double-blind, placebo-controlled study comprised of three periods  The first period of the study is an observational 14-week run-in period during which patients’ blood pressure, kidney function, degree of hematuria, and proteinuria will be measured. Patients will not receive study drug (cemdisiran or placebo) during this time. …

  • 99 views
  • 23 Nov, 2020
  • 2 locations
featured
Myelofibrosis

Myelofibrosis

  • 532 views
  • 08 Nov, 2020
  • 1 location
featured
Hyperbaric Oxygen (HBO) Therapy for Traumatic Brain Injury

Hyperbaric Oxygen (HBO) Therapy for Traumatic Brain Injury

  • 3822 views
  • 25 Mar, 2021
  • 1 location
featured
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

aplastic anemia
anemia studies
myelodysplastic syndrome (mds)
anemia
myelodysplastic syndromes
  • 123 views
  • 22 Dec, 2020
  • 1 location
Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

treatment as second-line therapy for subjects with ET who have had a suboptimal or failed response to HU.

neutrophil count
ropeginterferon alfa-2b
anagrelide
thrombosis
interferon
  • 0 views
  • 20 Mar, 2021
  • 51 locations
Adj. Dyn. Marker-adjusted Personalized Therapy Comparing Abemaciclib + SOC ET vs. SOC ET in Clinical or Genomic High Risk HR+/HER2- EBC

, will be eligible for the study. This patient group is currently offered a standard of care chemotherapy plus endocrine therapy (ET). The study investigates whether the patient group with high-risk

  • 0 views
  • 25 Jan, 2021
  • 3 locations
Adj. Marker-adjusted Personalized Therapy Comparing ET+Ribociclib vs Chemotherapy in Intermediate Risk HR+/HER2- EBC

The study investigates, whether the patient group with intermediate-risk early breast cancer benefits from treatment with ribociclib in combination with endocrine therapy compared to standard-of-care chemotherapy (followed by adjuvant endocrine therapy).

breast cancer
toremifene
cancer
neutrophil count
luminal
  • 0 views
  • 24 Jan, 2021
  • 8 locations
Regimens Comparison for Breast Cancers of Positive Lymph Nodes

To compare the efficacy and safety of EC-T and ET regimen as adjuvant treatment of breast cancer patients with positive lymph nodes

immunostimulant
paclitaxel
epirubicin
cancer surgery
  • 6 views
  • 08 Nov, 2020
  • 1 location
Anatomical Radiological and Biomechanical Examination of Athletic Groin Pain Patients and Physical Therapy Intervention

Athletic groin pain (AGP) is a chronic condition common in multi-directional sports (Walden et al. 2007, Robinson et al. 2004, Murphy et al. 2012). It is a complex injury with a challenging

  • 0 views
  • 21 Jan, 2021
  • 1 location
Fragility and Adapted Physical Activity

d'pinay et al., 1999) in three categories: independent, frail and dependent (HAS, 2005). Frailty is generally considered as a state that precedes dependent status and, unlike the latter, is still

  • 0 views
  • 23 Jan, 2021
  • 1 location