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Found 365 clinical trials
Chemoradiotherapy in Elderly Patients With Oesophagus Cancer (OSAGE)

Management of elderly patient with cancer is a therapeutic challenge and a public health problem. The mean age of esophageal cancer is 64.5 years and 72.1 years in men and women respectively

ebrt
chemoradiotherapy
esophagus cancer
external beam radiotherapy
esophageal cancer
  • 5 views
  • 15 Jun, 2022
  • 1 location
Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer, Esophageal Cancer and Liver Cancer

This trial is an investigator-initiated, single-center, open-label, single-arm exploratory study of mRNA neoantigen tumor vaccine in the treatment of advanced gastric cancer, esophageal cancer

liver metastasis
cancer chemotherapy
platelet count
measurable disease
antineoplastic agents
  • 0 views
  • 25 Mar, 2022
  • 1 location
AN0025 and Chemoradiotherapy Combination in Esophageal Cancer

advanced/locally recurrent esophageal cancer.

squamous cell carcinoma
chemoradiotherapy
recurrent esophageal cancer
esophagus cancer
carcinoma
  • 0 views
  • 21 Jul, 2022
  • 1 location
Endoscopic Assisted Calcium Electroporation in Esophageal Cancer

In this pilot study, patients with non-curable esophageal cancer will be treated with endoscopic assisted calcium electroporation (CaEP). CaEP is a novel cancer treatment where intratumoral

esophagus cancer
calcium
cancer treatment
  • 0 views
  • 24 Mar, 2022
  • 1 location
TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer (TRAP-2)

Despite treatment according to the CROSS-regimen, median overall survival is less than four years (2.3 QALYs). The burden of disease is within the highest category (0.71 to 1.0). Also, no targeted treatment options are currently available, hampering personalized treatment for this patient population. TRAP-2 aims to address these needs by …

HER2
endoscopic ultrasound
primary tumor
carboplatin
paclitaxel
  • 0 views
  • 10 Jul, 2022
  • 1 location
Teripalimab Plus Chemotherapy in Local Advanced Esophageal Cancer

The prognosis of locally advanced esophageal squamous cell carcinoma is poor,the role of chemotherapy as neoadjuvant therapy in locally advanced esophageal cancer has been established, which can

squamous cell carcinoma
unresectable esophageal cancer
squamous cell carcinoma of esophagus
adjuvant therapy
esophagus cancer
  • 1 views
  • 20 Feb, 2022
  • 1 location
CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer

The objective of this study is to evaluate the efficacy and safety of concurrent chemoradiotherapy combined with Itraconazole in patients with locally adcvanced esophageal squamous cancer

squamous cell carcinoma
esophageal carcinoma
chemoradiotherapy
squamous cell carcinoma of esophagus
measurable disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
Chemoradiotherapy Plus Immunotherapy Followed by Surgery for Esophageal Cancer

Neoadjuvant chemoradiotherapy is recommended as standard therapy for resectable esophageal cancer. The recurrence rate after surgery following neoadjuvant chemoradiotherapy is about 35%. Whether

  • 0 views
  • 08 Mar, 2021
  • 1 location
Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer

This is a randomized, controlled, multi-center, open trial, unresectable locally advanced or metastatic esophageal squamous cell carcinoma patients that failed at least second-line treatment and overexpressed EGFR were enrolled and randomly assigned to the experimental group and control group at a 1: 1 ratio.,who received Larotinib and the chemotherapy regimen …

squamous cell carcinoma
recurrent esophageal cancer
irinotecan
EGFR
esophagus cancer
  • 0 views
  • 17 Jul, 2021
  • 2 locations
Hypoxia Imaging for Esophageal Cancer to Guide Personalized Radiation Therapy (PIONEER)

This is a Phase I trial evaluating the safety of personalized radiation therapy based on levels of hypoxia identified on FMISO-PET and MRI. All patients will receive a baseline FMISO PET and MRI to identify levels of hypoxia. Patients with tumor hypoxia will receive a higher dose of radiation therapy. …

esophagus cancer
  • 0 views
  • 27 Jun, 2022
  • 1 location