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Found 366 clinical trials
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

The study is a phase 2 non-randomized, open-label, multi-cohort, multi-center study assessing the clinical benefit of SAR444245 (THOR-707) combined with other anticancer therapies for the treatment of participants aged 18 years and older with advanced and metastatic gastrointestinal cancer. This study is structured as a master protocol for the investigation …

measurable disease
cetuximab
pembrolizumab
esophageal cancer
gastrointestinal cancer
  • 5 views
  • 05 Aug, 2022
  • 36 locations
A Study of KF-0210 in Advanced Solid Tumors Patients

The purpose of this Phase I, Multi-Center, Open-Label Study is to evaluate the safety, tolerability, Pharmacokinetics, Pharmacodynamics and anti-tumor activity of KF-0210 in participants with advanced solid tumors. The study will be conducted in two parts: phase Ia, and phase Ib.

measurable disease
atezolizumab
  • 5 views
  • 11 Sep, 2021
  • 1 location
Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

This is a Phase 1, non-randomized, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors.

erbb2
measurable disease
progesterone receptor
ovarian cancer
cancer chemotherapy
  • 0 views
  • 23 May, 2022
  • 5 locations
Longitudinal Oral Microbiome Sampling for BE

This is a longitudinal cohort study to assess the impact of repeated sampling of an oral microbiome signature for Barrett's esophagus (BE). Potential participants will be identified through chart review of patients who have had an endoscopy in the past three years.

intestinal metaplasia
Accepts healthy volunteers
endoscopy
metaplasia
  • 10 views
  • 01 Dec, 2021
  • 2 locations
Comparison of Early Outcomes of Minimally Invasive Surgery for Oesophageal Replacement Versus Open Surgery in Children

a comparative prospective study of postoperative between minimally invasive and open surgery complications for esophageal replacement in children

  • 0 views
  • 25 Jan, 2021
  • 1 location
Volatile Organic Compounds for the Assessment of Liver Disease (VOCAL)

This study aims to determine whether a breath test could be used for early detection of hepatic fibrosis, cirrhosis or hepatocellular carcinoma. Patients who are attending for a planned liver outpatient services or investigations will be approached to provide a breath sample. Multi platform mass spectrometry analysis will be performed …

liver disease
hepatic fibrosis
Accepts healthy volunteers
cancer
hepatocellular carcinoma
  • 0 views
  • 25 May, 2022
  • 1 location