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Found 31 clinical trials
Featured trial
Eosinophilic Esophagitis Research Study

The purpose of this study is to see if CC-93538 is safe and effective as a possible treatment for EoE. To do this, a comparison will be made between subjects who receive CC-93538 and subjects who receive a placebo (a ‘dummy treatment’ that looks like CC-93538 but contains no active …

  • 0 views
  • 14 Jan, 2022
  • 1 location
EoE RCT Fluticasone and Omeprazole vs Fluticasone Alone

The purpose of this study is to evaluate the efficacy of combination therapy with omeprazole and swallowed fluticasone vs fluticasone therapy and placebo in the treatment of Eosinophilic Esophagitis (EoE) in children and adults. This study will be a double-blinded, randomized controlled trial. The primary outcome measured will be histologic …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Exposure Measurements and Interventions for Aerosol Produced by Gastrointestinal Endoscopy

Study objective: To clarify the risk of exposure to the exhaled aerosol droplets from patients for medical staffs during digestive endoscopy via labelling the oral mucosa with vitamin B2 solution, and evaluate the protective efficacy of personal protective equipment. Study design: This is a prospective randomized controlled study.

  • 0 views
  • 27 Jul, 2022
  • 1 location
EoE Food Desensitization

This is a single-center, prospective, pilot clinical trial in which children ages 3-17 years with eosinophilic esophagitis (EoE) who have a known food that triggers EoE flares receive oral desensitization with that specific food antigen, followed by reintroduction of that food into the diet. The purpose of this study is …

  • 5 views
  • 05 Jul, 2021
  • 1 location
Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE)

This study will enroll participants who have been diagnosed with Eosinophilic Esophagitis (EoE). Upon study enrollment, the participant will begin a proton pump inhibitor (PPI), Omeprazole 20mg twice daily. After taking Omeprazole for four weeks, the participant will have a Transnasal Endoscopy, and biopsies will be taken to determine the …

endoscopy
omeprazole 20 mg
proton pump inhibitors
  • 1 views
  • 09 Aug, 2022
  • 1 location
Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding

Peptic ulcer bleeding is a common emergency for patients who need therapeutic endoscopy. According to international guidelines and Taiwan consensus, the standard therapy included proton pump inhibitor (PPI) and endoscopic therapy. For high-risk peptic ulcers, such as active spurting, oozing bleeding, a nonbleeding visible vessel or ulcers with adherent clots, …

  • 0 views
  • 13 Jun, 2022
  • 1 location
Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of GEV in Patients With Cirrhosis

This is a non-interventional diagnostic accuracy study. Using EGD as the golden standard, to assess the accuracy of the ds-MCE in identifying and grading gastroesophageal varices in patients undergoing screening or surveillance for gastroesophageal varices. And the efficacy of the ds-MCE in detecting various pathological changes of cirrhosis in small …

cirrhosis
gastroesophageal varices
endoscopy
varicose veins
  • 0 views
  • 17 Feb, 2022
  • 2 locations
A Multicenter Case-Control Study of the Efficacy of EsoGuard on Samples Collected Using EsoCheck, Versus Esophagogastroduodenoscopy, for the Diagnosis of Barrett's Esophagus With and Without Dysplasia, and for Esophageal Adenocarcinoma (ESOGUARDBE2)

Barrett's Esophagus (BE), with or without dysplasia, and esophageal adenocarcinoma (EAC) as compared to Esophagogastroduodenoscopy (EGD) plus biopsies in both confirmed cases of BE/EAC and in controls

gastroesophageal reflux disease
intramucosal adenocarcinoma
gastroesophageal reflux
body mass index (bmi)
dysplasia
  • 334 views
  • 18 Sep, 2022
  • 27 locations
Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial

A randomized clinical trial comparing endoscopic per-oral pyloromyotomy (POP) versus a control sham intervention (diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption) in

anesthesia
upper endoscopy
gastric emptying study
endoscopy
pyloromyotomy
  • 0 views
  • 22 Dec, 2021
  • 1 location
Purastat Prevention Delayed Bleeding Duodenum

presence of active bleeding or high risk stigma of bleeding will be observed on an esophagogastroduodenoscopy (EGD) performed 1 day after the duodenal EMR. Furthermore the presence of clinical signs of

  • 0 views
  • 26 Jan, 2021
  • 1 location