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Found 45 clinical trials
Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma

Neoadjuvant chemoradiotherapy followed by surgery has been the standard modality for locally advance esophageal carcinoma. According to CROSS study, the pathological complete remission rate achieved by paclitaxel and carboplatin with 41.4 Gy/23f was 49% for esophageal squamous cell carcinoma. But the 10-year overall survival rate was only 38%. How to …

  • 0 views
  • 13 May, 2022
  • 1 location
Balloon Dilation Methods for Benign Esophageal Stricture

This is the first head to head, prospective, randomized, double-blind clinical trial comparing two different approaches of balloon dilation (standard versus progressive dilation) for benign esophageal strictures. A retrospective study on patients with benign esophageal strictures that underwent balloon dilation using the proposed technique found considerable symptomatic improvement in dysphagia. …

  • 7 views
  • 31 Oct, 2021
  • 1 location
Chemoradiotherapy Followed by Planned Surgery or by Surveillance and Surgery Only When Needed for Oesophageal Cancer (NEEDS)

outcomes after neoadjuvant chemoradiotherapy with subsequent esophagectomy to definitive chemoradiotherapy with surveillance and salvage esophagectomy as needed in patients with resectable locally advanced

cancer
calcium
squamous cell carcinoma
esophagus cancer
esophagectomy
  • 6 views
  • 23 Apr, 2022
  • 9 locations
Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP)

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

bypass surgery
cancer
vascular surgical procedures
stroke
coronary artery bypass graft
  • 12 views
  • 12 Apr, 2022
  • 14 locations
Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy

This research study is a phase III randomized trial to study the value of the addition of a pyloroplasty procedure versus no pyloroplasty procedure during the performance of esophagectomy

  • 0 views
  • 23 Mar, 2022
  • 1 location
Robot-assisted Esophagectomy Versus Conventional Thoracoscopic Esophagectomy

This is the first randomized controlled study to compare the robot-assisted esophagectomy (RAE) to minimally invasive conventional thoracoscopic esophagectomy (CTE). The aim of this trial is to

carcinoma
squamous cell carcinoma
esophagectomy
  • 6 views
  • 23 Jan, 2021
  • 6 locations
Robotic-assisted Esophagectomy vs. Video-Assisted Thoracoscopic Esophagectomy(REVATE) Trial

The investigators will assess the adequacy of nodal dissection along the recurrent laryngeal nerve performed with robot-assisted versus video-assisted thoracoscopic esophagectomy in patients

carcinoma
cancer
squamous cell carcinoma
esophagus cancer
esophagectomy
  • 3 views
  • 01 Feb, 2022
  • 1 location
Laparoscopic Ischemic Conditioning Prior to Esophagectomy (ISCON)

upon UCS and NASCET calcification scores on pre-op CT-scan. In these patients, laparoscopic ischemic conditioning is performed 12-18 days before an Ivor-Lewis esophagectomy. The primary outcome is all

adenocarcinoma
squamous cell carcinoma
esophagectomy
ivor
indocyanine green
  • 3 views
  • 22 Mar, 2022
  • 2 locations
Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy .

This is a randomized controlled trial designed to compare robot-assisted thoracic approach with open transthoracic esophagectomy (Ivor Lewis technique) as a surgical treatment for resectable

  • 0 views
  • 28 Jan, 2021
  • 1 location
A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy

Surgery is still the main treatment for esophageal cancer, however, the complication and mortality rate of open esophagectomy is high. As a result, the thoracoscopic- laparoscopic minimally

cancer
esophagectomy
esophagus cancer
ivor
esophageal cancer
  • 0 views
  • 23 Jan, 2021
  • 1 location