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Found 385 clinical trials
Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center Prospective Open One Arm Exploratory Clinical Study

To purpose of this study is to access the safety and efficacy of neoadjuvant Immunotherapy (PD-1 / PD-L1) combined with chemotherapy for locally advanced thoracic esophageal squamous cellcarcinoma.

squamous cell carcinoma
esophagus cancer
cancer
chemoradiotherapy
neutrophil count
  • 0 views
  • 07 Sep, 2021
  • 1 location
The Detection of Barrett's Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy (Refleeve)

Severe Gastroesophageal reflux disease (GERD) leading to a chronic aggression of esophagus mucosa, called Barrett's esophagus is a main complication of Sleeve gastrectomy for morbid obesity. Barrett's esophagus is considered as a early stage of neoplastic transformation to adenocarcinoma. Since this last years, six european bariatric centers have adopted the …

endoscopy
esophagogastroduodenoscopy
barrett's esophagus
sleeve gastrectomy
  • 15 views
  • 05 Mar, 2022
  • 1 location
Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes in Non-metastatic, Non-recurrent Lung and Esophageal Cancer Patients

This trial studies cardiac changes after radiation or chemo-radiation for the treatment of lung or esophageal cancer that has not spread to other places in the body (non-metastatic) or has not

  • 0 views
  • 21 Mar, 2022
  • 1 location
Influence of Radiotherapy and Chemotherapy in the Value of Peripheral Blood Lymphocyte Subsets Among Thoracic Cancer

lung cancer, esophageal squamous cell carcinoma and thymic epithelial carcinoma underwent radiotherapy with or without chemotherapy.

squamous cell carcinoma
esophagus cancer
cancer
lung carcinoma
direct bilirubin
  • 0 views
  • 24 Jan, 2021
  • 1 location
Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer

The study's aim is to define imaging and molecular bio-markers for prediction of radiotherapy response of squamous cell carcinomas, in an early treatment phase.

carcinoma
dental caries
squamous cell carcinoma
cancer
cavities
  • 29 views
  • 09 Oct, 2021
  • 4 locations
Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy

Inhibitors of the programmed cell death protein 1 (PD-1)/PD-L1 immune checkpoint signaling pathway are already approved in the treatment of various tumor entities in relapsed or metastatic stages. Different exploratory trials suggest that the combination of radiotherapy and PD-1/PD-L1 inhibitors is highly effective, especially in oligometastatic stages and if all …

solid tumour
immunomodulator
programmed cell death protein 1
programmed cell death 1 ligand 1
  • 0 views
  • 28 May, 2021
  • 1 location
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Circulating and disseminated tumor cell (CTC/DTC) and circulating cell-free (cf) DNA isolation from the blood, urine and bone marrow will increase understanding of cancer spread and advance knowledge …

Accepts healthy volunteers
cancer surgery
cancer
metastasis
x-rays
  • 68 views
  • 23 Feb, 2022
  • 1 location
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Also, early detection of lung cancer with low dose CT screening may cure patients at an early stage. Circulating and disseminated tumor cell (CTC/DTC) and circulating cell-free (cf) …

cancer surgery
lung carcinoma
cancer
metastasis
skin cancer
  • 24 views
  • 11 Apr, 2022
  • 1 location
Changes Associated With H. Pylori and Gastric Carcinogenesis

This is a research study for patients who currently have or previously had an H. pylori infection or who have gastric or esophageal cancer and who plan to undergo an endoscopy as part of their

gastric cancer
endoscopy
cancer
  • 101 views
  • 08 Jul, 2021
  • 1 location
Nutrition in Gastrointestinal Tumors

Malnutrition and loss of muscle mass frequently occur in patients undergoing chemotherapy and can negatively effect therapy outcome. Especially patients with cancer of the gastrointestinal tract are often affected by malnutrition. Therefore, this study aims to examine changes in nutritional status of patients with cancer of the gastrointestinal tract during …

cancer
cancer chemotherapy
gastrointestinal tumor
cytostatic
gastrointestinal cancer
  • 0 views
  • 09 Nov, 2021
  • 1 location