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Found 24 clinical trials
Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC) (PiSCATIN)

transplantation, cholangiocarcinoma or bleeding from esophageal varices. Subjects will be randomized (1:1) between Simvastatin and placebo.

  • 4 views
  • 06 May, 2022
  • 11 locations
SHAPE of Portal Hypertension in Children

-threatening complications, the most frequent of which is bleeding from esophageal varices. In children, variceal bleeds are associated with mortality rates of 1-3 %, while life-threatening complications have

  • 0 views
  • 25 Mar, 2022
  • 1 location
Dual Energy CT as a Noninvasive Method to Screen for Gastroesophageal Varices

varices, and allows for assessment of para-esophageal varices, varices in other body locations, ascites, other signs of portal hypertension, patency of liver vasculature, and detection, diagnosis and

  • 0 views
  • 24 Jul, 2022
  • 1 location
Apixaban for Intrahepatic Non Cirrhotic Portal Hypertension (APIS)

Intrahepatic non-cirrhotic portal hypertension (INCPH) is a rare disease mostly affecting adults in their forties, characterized by portal hypertension related to alterations of intrahepatic microcirculation in the absence of cirrhosis.The only therapeutic options currently available for patients with INCPH include prophylaxis for variceal bleeding using betablockers and/or endoscopic band ligation …

  • 3 views
  • 05 Apr, 2022
  • 1 location
Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

compared with placebo in patients with nonalcoholic steatohepatitis (NASH) cirrhosis and clinical signs of portal hypertension but without esophageal varices at baseline.

oophorectomy
hypertension
varices
MRI
statin
  • 351 views
  • 26 Jul, 2022
  • 128 locations
Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of GEV in Patients With Cirrhosis

This is a non-interventional diagnostic accuracy study. Using EGD as the golden standard, to assess the accuracy of the ds-MCE in identifying and grading gastroesophageal varices in patients undergoing screening or surveillance for gastroesophageal varices. And the efficacy of the ds-MCE in detecting various pathological changes of cirrhosis in small …

varicose veins
gastroesophageal varices
endoscopy
cirrhosis
  • 0 views
  • 17 Feb, 2022
  • 2 locations
Carvedilol for Prevention of Esophageal Varices Progression (Carvedilol)

Carvedilol has been shown to be more potent in decreasing portal hypertension to propranolol. But the efficacy of carvedilol to delay the growth of esophageal varices in chronic hepatitis B

hepatitis
varicose veins
hypertension
carvedilol
esophageal varices
  • 4 views
  • 24 Mar, 2022
  • 6 locations
Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices

The cumulative risk of refractory ascites is in the order of 20% within five years of the development of ascites. An elevated sinusoidal pressure is essential for the development of ascites, as fluid accumulation does not develop at portal pressure gradient below 8 mm Hg, and rising corrected sinusoidal pressure …

hypertension
vasopressin
ascites
cytokines
vasodilatation
  • 0 views
  • 06 Nov, 2021
  • 1 location
Comparison of 24-hours Versus 72-hours of Octreotide Infusion in Preventing Early Rebleed From Esophageal Varices (LOVARB)

This study evaluates the safety and efficacy of 24-hour vs 72-hour octreotide infusion after variceal banding in cirrhotic patients with bleeding esophageal varices.

esophageal varices
  • 110 views
  • 12 Feb, 2022
  • 7 locations
The Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric Varices

worsening of esophageal varices. The present study was designed to evaluate the effect of post-BRTO propranolol adminstration on the change of esophageal varices.

varicose veins
cirrhosis
esophageal varices
portosystemic shunt
gastric varices
  • 8 views
  • 30 Nov, 2021
  • 1 location