Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 13 clinical trials
Monopolar and Bipolar Current RFA Knife in POEM

Per Oral Endoscopic Myotomy (POEM) is performed for various esophageal muscular disorders, including achalasia and other spastic esophageal conditions. It is performed with the standard endoscope and involves dissecting the esophageal muscle sphincter. The procedure is typically completed using standard monopolar energy, which are effective, but can be associated with …

  • 0 views
  • 21 Apr, 2022
  • 1 location
Per Oral Endoscopic Myotomy (POEM) and Prolonged Dilatation (PRD) for Achalasia

Achalasia is an esophageal motility disorder, which leads to clinical symptoms such as dysphagia, regurgitation, chest pain and consecutive weight loss. Although conventional treatment

chest pain
esophageal motility
dysphagia
regurgitation
motility disorder
  • 160 views
  • 21 Jan, 2021
High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux

are assessed for preoperative ineffective esophageal motility (IEM). The main hypothesis is, that preoperative oesophageal motility disorders, especially hypo-contractility or failed

  • 0 views
  • 03 Dec, 2021
  • 1 location
Assessment of the Neuro-glio-epithelial Unit (NGEU) in Biopsies Taken During Peroral Endoscopic Myotomy (POEM) for Achalasia: a Feasibility and Safety Study. (Achalaglie)

Achalasia is a primary esophageal motility disorder characterized on high-resolution manometry (HRM) studies by 100% failed peristalsis and elevated integrated relaxation pressure of the lower

esophageal motility
poem procedures
peroral endoscopic myotomy
prealbumin
motility disorder
  • 66 views
  • 24 Mar, 2022
  • 1 location
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.

  • 0 views
  • 19 Apr, 2021
  • 1 location
Esophagogastric Junction Distensibility During Hiatal Hernia Repair

The investigators aim to ascertain the effects of hiatal hernia repair and fundoplication on the distensibility of the esophagogastric junction (EGJ) as measured by FLIP topography/impedance planimetry. The investigators also aim to assess for any correlation between values of EGJ distensibility and GERD related quality of life (QOL) and dysphagia …

  • 0 views
  • 13 May, 2022
  • 1 location
Use of EndoFLIP and Manometry Prior to G-POEM

The purpose of this study is to assess physiologic response of therapy in patients with refractory gastroparesis undergoing Gastric per-oral endoscopic myotomy (G-POEM) using endoscopic functional lumen imaging probe (EndoFLIP) and antroduodenal manometry (ADM). Refractory gastroparesis will be defined as having delayed gastric emptying at four hours (>10% retention of …

  • 0 views
  • 24 Apr, 2021
  • 1 location
The Effect of Positional Therapy on Symptoms of Gastroesophageal Reflux Disease: A Prospective Pilot Study

Gastroesophageal reflux disease related symptoms are reported by 10-20% of the adult population and of those 50-75% report symptoms during sleep time. The prevalence of nocturnal GERD (nGERD) is estimated to be about 25% in general population. nGERD causes sleep fragmentation, difficulty falling asleep, daytime sleepiness, reduced work productivity and …

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
  • 1 location
Chicago Classification Normative Metrics in a Healthy Russian Cohort According to High-resolution Esophageal Manometry

High resolution esophageal manometry normative values are still need to be studied in different populations and with the use of solid-state and water-perfused systems. There has been no study on the subject in healthy Russian population yet.

Accepts healthy volunteers
  • 0 views
  • 09 Feb, 2022
  • 3 locations
Peroral Endoscopic Myotomy (POEM) for the Treatment of Achalasia (POEM)

Achalasia is a chronic disease of altered esophageal motility with resulting functional obstruction to the passage of food leading to poor quality of life and significant morbidity. The two main

chronic disease
gastroesophageal reflux
chest pain
esophageal motility
dysphagia
  • 575 views
  • 03 Jun, 2022
  • 1 location