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Found 395 clinical trials
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A Phase 1 Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02385 in Participants With Select Advanced Malignancies

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.  This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02385 at the protocol-defined starting dose administered every 2 weeks (Q2W), with dose …

ovarian cancer
metastatic cervical cancer
urothelial carcinoma
carcinoma
  • 156 views
  • 23 Nov, 2020
  • 4 locations
featured
A Phase 1, Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02390 in Participants With Select Advanced Malignancies

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02390 in participants with advanced malignancies. This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02390 at the protocol-defined starting dose administered every 2 weeks (Q2W), with …

cancer
advanced cancer
  • 128 views
  • 14 Dec, 2020
  • 4 locations
Combination Chemotherapy in Treating Patients With Esophageal Cancer

yet known which regimen of combination chemotherapy is more effective in treating esophageal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of

tumor cells
conventional surgery
epirubicin
cancer
combination chemotherapy
  • 31 views
  • 07 Nov, 2020
  • 1 location
Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial

Surgery is the standard treatment for esophageal (food pipe) cancer. Esophageal cancer is known to spread to the lymph nodes (glands) adjacent to the esophagus. The extent of lymph nodes

lymphadenectomy
adenocarcinoma
esophagectomy
cancer
esophageal cancer
  • 15 views
  • 07 Nov, 2020
  • 1 location
Study of SHR-1210 in Combination With Chemotherapy in Advanced Esophageal Cancer

1L therapy for advanced esophageal cancer patients in China. SHR-1210 is a humanized anti-PD1 IgG4 monoclonal antibody.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus

The purpose of this study is to determine the Maximum Tolerated Dose (MTD) of olaparib in combination with radical radiotherapy in patients with oesophageal cancer who are unsuitable for

chemoradiotherapy
cancer
neutrophil count
esophagus cancer
platelet count
  • 2 views
  • 08 Nov, 2020
FOLFIRI as Second Line Chemotherapy for Metastatic Esophageal Carcinoma

This phase study was designed to evaluate the efficacy and safety of FOLFIRI as second-line treatment for metastatic esophageal carcinoma.

  • 7 views
  • 23 Jan, 2021
  • 1 location
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer

chemotherapy (CDDP, 5-FU) plus radiation therapy in treating patients with unresectable, advanced or recurrent esophageal cancer.

chemoradiotherapy
peptide vaccine
recurrent esophageal cancer
cancer
vaccine therapy
  • 11 views
  • 07 Nov, 2020
  • 1 location
Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal Cancer

This study is multi-center randomized phase III one to evaluate the difference in local-control and survival rate between patients receiving concurrent chemoradiotherapy combined Tarceva or not.

carcinoma
chemoradiotherapy
paclitaxel
esophageal carcinoma
cancer
  • 4 views
  • 07 Nov, 2020
  • 1 location
S-1 Cisplatin and Radiation Therapy in Treating Patients With Stage IIA Stage III or Stage IVA Esophageal Cancer That Can Be Removed by Surgery

phase II trial is studying how well giving S-1 and cisplatin together with radiation therapy works in treating patients with stage IIA, stage III, or stage IVA esophageal cancer that can be

x-rays
tumor cells
potassium
combination chemotherapy
cancer
  • 3 views
  • 07 Nov, 2020
  • 1 location