Found 395 clinical trials
A Phase 1 Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02385 in Participants With Select Advanced Malignancies
The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies. This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02385 at the protocol-defined starting dose administered every 2 weeks (Q2W), with dose …
- 156 views
- 23 Nov, 2020
- 4 locations
A Phase 1, Open-Label, Dose-Escalation, Safety and Tolerability Study of INCAGN02390 in Participants With Select Advanced Malignancies
The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02390 in participants with advanced malignancies. This investigational intervention treatment uses a single biological drug and is conducted in two parts. Part 1: INCAGN02390 at the protocol-defined starting dose administered every 2 weeks (Q2W), with …
- 128 views
- 14 Dec, 2020
- 4 locations
Combination Chemotherapy in Treating Patients With Esophageal Cancer
yet known which regimen of combination chemotherapy is more effective in treating esophageal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of
- 31 views
- 07 Nov, 2020
- 1 location
Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial
Surgery is the standard treatment for esophageal (food pipe) cancer. Esophageal cancer is known to spread to the lymph nodes (glands) adjacent to the esophagus. The extent of lymph nodes
- 15 views
- 07 Nov, 2020
- 1 location
Study of SHR-1210 in Combination With Chemotherapy in Advanced Esophageal Cancer
1L therapy for advanced esophageal cancer patients in China. SHR-1210 is a humanized anti-PD1 IgG4 monoclonal antibody.
- 0 views
- 22 Jan, 2021
- 1 location
Radiotherapy & Olaparib in COmbination for Carcinoma of the Oesophagus
The purpose of this study is to determine the Maximum Tolerated Dose (MTD) of olaparib in combination with radical radiotherapy in patients with oesophageal cancer who are unsuitable for
- 2 views
- 08 Nov, 2020
FOLFIRI as Second Line Chemotherapy for Metastatic Esophageal Carcinoma
This phase study was designed to evaluate the efficacy and safety of FOLFIRI as second-line treatment for metastatic esophageal carcinoma.
- 7 views
- 23 Jan, 2021
- 1 location
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer
chemotherapy (CDDP, 5-FU) plus radiation therapy in treating patients with unresectable, advanced or recurrent esophageal cancer.
- 11 views
- 07 Nov, 2020
- 1 location
Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal Cancer
This study is multi-center randomized phase III one to evaluate the difference in local-control and survival rate between patients receiving concurrent chemoradiotherapy combined Tarceva or not.
- 4 views
- 07 Nov, 2020
- 1 location
S-1 Cisplatin and Radiation Therapy in Treating Patients With Stage IIA Stage III or Stage IVA Esophageal Cancer That Can Be Removed by Surgery
phase II trial is studying how well giving S-1 and cisplatin together with radiation therapy works in treating patients with stage IIA, stage III, or stage IVA esophageal cancer that can be
- 3 views
- 07 Nov, 2020
- 1 location