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Found 83 clinical trials
Efficacy and Safety of an Innovative Chinese Herbal Formula for the Treatment of Gout: A Double-blind, Randomized, Placebo-Controlled Trial

Gout is a chronic disease of deposition of monosodium urate crystals, which form in the presence of increased urate concentrations. Gout is closely related to hyperuricaemia. Urate deposits in the joint, causing joint swelling, pain, movement disorders, affecting a significant portion of the population worldwide annually. The underlying pathophysiology of …

  • 22 Oct, 2022
  • 1 location
Silicone Taping for the Improvement of Abdominal Donor Site Scars

This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two …

  • 05 Sep, 2023
  • 1 location
Regional Blocks for Lateral Condyle Fractures

The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning. Patients will be randomized into one of two groups. Group 1 will receive an infraclavicular nerve block to the affected extremity by a …

postoperative pain
nerve block
  • 03 Mar, 2022
  • 1 location
Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules

Xerostomia is defined as the subjective sensation of dry mouth, and may be associated with a reduction in saliva secretion and composition. It is one of the most common complaints found in patients after irradiation in the head and neck area. This complaint is found in a large majority of …

  • 05 Jan, 2022
  • 1 location
Improving Visual Field Deficits With Noninvasive Brain Stimulation

This is a randomized, pilot interventional study in participants with visual field deficit (VFD) caused by cortical lesion. Damage to the primary visual cortex (V1) causes a contra-lesional, homonymous loss of conscious vision termed hemianopsia, the loss of one half of the visual field. The goal of this project is …

  • 27 Aug, 2023
  • 1 location
Human Immune Response to Ixodes Scapularis Tick Bites

Background Each year, the number of cases of tick-borne diseases increases. The deer tick (Ixodes scapularis) is the vector of at least 7 pathogens that cause human diseases, including Lyme disease. Researchers want to learn more to help them develop vaccines against ticks in the future. Objective To learn how …

tick bite
tick-borne diseases
Accepts healthy volunteers
skin biopsy
blood draw
  • 30 Aug, 2023
  • 1 location
Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune system makes a mistake and attacks the body. Some people with APECED have a type of hair loss called alopecia areata (AA). No drugs are approved to treat AA. Objective …

bilateral tubal ligation
cervical cap
areata alopecia
graft-versus-host disease
  • 15 Aug, 2023
  • 1 location
The Use of Autologous Amniotic Fluid at Cesarean Wound Closure

The purpose of this study is to determine the feasibility of collecting amniotic fluid at delivery that will be immediately processed and then applied as a spray to the various layers of cesarean wound closure.

cesarean section
Accepts healthy volunteers
  • 06 Apr, 2023
  • 1 location
DExterous Hand Control Through Fascicular Targeting (DEFT) - (Human Subjects)

Our goal is to temporarily implant the following groups for 180 +/- 30 days: Five human partial hand amputees (amputated at the level of the hand) with 2 FAST-LIFE electrodes, one inserted into the motor fascicle of the ulnar nerve and the other into the sensory fascicle. Five human hand …

  • 23 Mar, 2022
  • 1 location
Maintenance in Autologous Stem Cell Transplant for Crohn's Disease (MASCT - CD)

Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant complications and discomfort in the stomach and intestines. Crohn's disease is a debilitating, incurable disease of immune cells; it affects almost 1 million people in the United States. CD is characterized by inflammation of the stomach and …

stem cell transplantation
certolizumab pegol
  • 21 Oct, 2022
  • 1 location