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Found 65 clinical trials
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(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 148 views
  • 08 Nov, 2020
  • 1 location
featured
Heartburn study, for people with non-erosive gastroesophageal reflux disease

A research study to evaluate the efficacy and safety of vonoprazan 10 mg, 20 mg, and 40 mg compared to placebo for relief of episodic heartburn in subjects with symptomatic non-erosive gastroesophageal reflux disease.

  • 0 views
  • 31 Mar, 2021
  • 1 location
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A research study for subjects with clinically significant heartburn

This study will assess the efficacy and safety of study drug, vonoprazan (20 mg once daily [QD]) compared to lansoprazole (30 mg QD) in the healing and relief of heartburn in subjects with endoscopically proven Erosive Esophagitis (EE).  

lansoprazole
esophagitis
  • 60 views
  • 23 Nov, 2020
  • 1 location
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker

Observation has pointed out, that osteitis present in the MRI scans, predicts bone erosion and that this in accordance with the concept by underlining the importance of bone marrow involvement

  • 0 views
  • 24 Jan, 2021
Transvaginal Mesh vs. Laparoscopic Colposacropexy- Study

(peri- and post-surgery complications, pain, erosion), objective efficacy (simplified POP-Q), and re-operation rate. Subjective outcome also includes the assessment of sexual satisfaction. Cost

  • 0 views
  • 25 Feb, 2021
  • 1 location
Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study

The purpose of this study is to establish the safety and feasibility of the Edwards SAPIEN 3 valve in subjects with mitral annular calcification (MAC) associated with mitral stenosis (MS) and/or mitral regurgitation who are at high-risk for mitral valve surgery or deemed inoperable due to the extent of calcification.

  • 60 views
  • 02 Feb, 2021
  • 7 locations
Arthroscopic Evaluation of Cartilage Regeneration After Opening-wedge High Tibial Osteotomy

Osteoarthritis of the knee is a common problem causing significant knee pain and disability. Medial compartment osteoarthritis is predisposed to by varus deformity of the knee. High tibial osteotomy is a well-established method for treatment of medial unicompartmental knee osteoarthritis and correction of varus deformity.

  • 0 views
  • 02 Aug, 2021
  • 2 locations
TSA vs RSA in Osteoarthritis

This study will compare total shoulder arthroplasty (TSA) reverse shoulder arthroplasty (RSA) procedures, in the context of a prospective, randomized-controlled trial to determine the optimal treatment in patients 65 years of age and older who have glenohumeral osteoarthritis.

  • 0 views
  • 23 May, 2021
  • 5 locations
Low-Dose Danazol for the Treatment of Telomere Related Diseases

Background DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to …

  • 57 views
  • 08 Apr, 2021
  • 1 location
The Use of Avaulta for Anterior Repair

Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age. Consequently, many surgical procedures have been developed in order to ensure sufficient support for the bladder, rectum or vaginal vault depending on the site of the defect. …

  • 4 views
  • 07 Nov, 2020
  • 1 location