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Found 42 clinical trials
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RTOG 0848: A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma.

RTOG 0848: A Phase III Trial Evaluating Both Erlotinib and Chemoradiation as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma.

  • 620 views
  • 08 Nov, 2020
  • 1 location
None
Tarceva Italian Lung Optimization tRial

The aim of this study is to assess the superiority of docetaxel in comparison to erlotinib in second line in wild-type EGFR tumour patients.

erlotinib
tarceva
docetaxel
EGFR
  • 57 views
  • 07 Nov, 2020
  • 47 locations
None
Study of IRX4204 With Erlotinib in Previously Treated Advanced NSCLC

and erlotinib will be studied using intra-patient dose escalation for dose levels 1 and 2. These study agents will be administered orally until progression of disease, unacceptable toxicities

brain metastases
tyrosine
ct scan
neutrophil count
cancer chemotherapy
  • 12 views
  • 24 Jan, 2021
  • 1 location
None
Study of 3D Radiotherapy With or Without Erlotinib (Tarceva ) in Patients With Localized Non-Small Cell Lung Cancer

A phase II, multicenter, randomized trial of 3D Radiotherapy versus 3D Radiotherapy and erlotinib (Tarceva®) in patients with localized-unresectable (IA-IIIB) non-small cell lung cancer

tarceva
measurable disease
erlotinib
  • 3 views
  • 07 Nov, 2020
  • 1 location
None
Erlotinib and Docetaxel in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Failure of One Chemotherapy Regimen

Erlotinib has demonstrated efficacy as a single agent in patients with NSCLC and the addition of erlotinib to chemotherapy has not achieved better results in the general population

cancer chemotherapy
secondary malignant neoplasm of liver
metastasis
neutrophil count
erlotinib
  • 1 views
  • 07 Nov, 2020
  • 6 locations
None
Hydroxychloroquine and Gefitinib to Treat Lung Cancer

as ZD1839) and erlotinib (Tarceva ®, formerly known as OSI-774). Both are small molecule orally-bioavailable tyrosine kinase inhibitors (TKIs) of the EGFR TK domain, and have been shown to

gefitinib
tyrosine
pleural effusion
iressa
growth factor
  • 39 views
  • 07 Nov, 2020
  • 1 location
None
A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases

kinase inhibitors (TKIs) such as Erlotinib and Gefinitib. The aim of this study is to compare the effects of Osimertinib alone versus SRS plus Osimertinib on intra-cranial disease control in EGFR

  • 50 views
  • 15 Mar, 2021
  • 15 locations
None
A Study of FWD1509 in Adults With Non-Small Cell Lung Cancer

The purpose of this study is to characterize the safety and tolerability of FWD1509 MsOH in advanced NSCLC patients and establish the maximum tolerable dose (MTD), recommended phase 2 dose (RP2D) in advanced NSCLC patients.

EGFR
kidney function test
neutrophil count
systemic therapy
measurable disease
  • 0 views
  • 10 Oct, 2021
  • 2 locations
None
Tailored Second Line Treatment by Epidermal Growth Factor Receptor (EGFR) Mutation in Patients With Advanced Lung Adenocarcinoma

Currently the investigators have two different classes of second-line treatment options in recurrent non-small Cell Lung Cancer (NSCLC). In chemotherapy, docetaxel and pemetrexed produced similar treatment efficacy outcomes, while pemetrexed had a better tolerability. In recent analysis of pemetrexed clinical studies, a strong treatment-by-histology interaction in overall survival and progression …

tyrosine
lung adenocarcinoma
measurable disease
alimta
kinase inhibitor
  • 9 views
  • 07 Nov, 2020
  • 1 location
None
Detection of EGFR Mutation in Malignant Pleural Effusion of Lung Cancer Patients and Cancer Cell Lines Establishment

1. Detection EGFR mutation of cancer cells from malignant pleural effusion. 2. Established the cancer cell lines with without EGFR mutation from malignant pleural effusion.

EGFR
pleural effusion
  • 7 views
  • 07 Nov, 2020