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Found 99 clinical trials
Pediatric Postoperative Analgesia Herniorrhaphy Study

This is a Phase 2, double-blind study in pediatric subjects undergoing inguinal herniorrhaphy.

bupivacaine
anesthesia
postoperative pain
herniorrhaphy
  • 9 views
  • 23 Jan, 2021
  • 1 location
Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery

This clinical trial studies how well hypnosedation works in relaxing and reducing the need for general anesthesia in patients who are undergoing breast cancer surgery. Hypnosedation is a technique that places patients under conscious sedation where they remain awake and numbed during surgery and involves the use of words and …

mastectomy
  • 1 views
  • 03 Feb, 2021
  • 2 locations
Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue (MICROBAT)

Patients affected by pheochromocytoma (PHEO) have brown-adipose tissue (BAT) hyperactivation. They perform, in routine settings, a FDG PET-CT scan. The high metabolic activity of BAT and its ability to consume both glucose and fatty acid suggest that it may have potential as a therapeutic target in the treatment of obesity. …

ct scan
18f-fdg
fdg pet/ct
pheochromocytoma
positron emission tomography/computed tomography
  • 0 views
  • 25 Jan, 2021
  • 1 location
Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of Anaphylaxis

Anaphylaxis is an acute serious allergic reaction, with multi-organ system manifestations caused by the release of chemical mediators and it is potentially fatal . Between 5% and 14% of patients may experience a recurrence of anaphylaxis 8-12 hours after the initial presentation, called biphasic (late-phase) . The mainstay of treatment …

  • 599 views
  • 25 Jan, 2021
  • 1 location
Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome

To improve pain control and decrease opioid requirements for subjects undergoing Total Shoulder Replacement.

bupivacaine liposome injection [exparel]
exparel
nerve block
total shoulder replacement
shoulder replacement
  • 0 views
  • 29 Jan, 2021
  • 1 location
Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block

The aim of this study is to study the analgesic efficacy of a continuous infusion of local anaesthetics for interscalene brachial plexus block after major shoulder surgery in the setting of multimodal analgesia, in order to determine whether the use of a catheter is still necessary in a contemporary practice.

ropivacaine
brachial plexus block
continuous infusion
local anesthetics
local anesthesia
  • 0 views
  • 25 Jan, 2021
  • 1 location
Optimizing Recovery in Abdominoplasty

The overall purpose of this study is to evaluate the analgesic efficacy of liposomal bupivacaine in optimizing pain control, minimizing the risk of postoperative nausea and vomiting (PONV), and improving recovery after abdominoplasty. This will be done by comparing intraoperative abdominal wall and incisional injection of bupivacaine to bupivacaine plus …

  • 0 views
  • 03 Feb, 2021
  • 2 locations
Comparison of TAP Anterior QL or ESP Block for Elective Cesarean Section

The purpose of this prospective single center, randomized study is to determine if ultrasound guided Transversus Abdominis Plane (TAP), Quadratus Lumborum (QL), and Erector Spinae Plane (ESP) blocks decrease opioid consumption in subjects undergoing elective cesarean section.

ropivacaine
elective cesarean delivery
transversus abdominis plane block
opioid
quadratus lumborum block
  • 0 views
  • 25 Jan, 2021
  • 1 location
The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology

The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures. Because patients who have undergone Fontan procedures rely on low pressures across the pulmonary vascular bed to maintain cardiac output, vasoactive agents that concomitantly increase …

vasopressin
  • 0 views
  • 25 Jan, 2021
  • 2 locations
Mechanisms for Activation of Beige Adipose Tissue in Humans

Mirabegron (Myrbetriq, Astellas) is a highly specific and well-tolerated 3 agonist marketed for overactive bladder. This trial will assess the effects of mirabegron on glucose tolerance and adipose tissue in prediabetic patients

  • 0 views
  • 26 Jan, 2021
  • 1 location