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Found 99 clinical trials
Diagnosis of Pheochromocytoma

The goal of this study is to develop better methods of diagnosis, localization, and treatment for pheochromocytomas. These tumors, which usually arise from the adrenal glands, are often difficult to detect with current methods. Pheochromocytomas release chemicals called catecholamines, causing high blood pressure. Undetected, the tumors can lead to severe …

positron emission tomography
iobenguane
ct scan
computed tomography
clonidine
  • 16 views
  • 03 Feb, 2021
  • 2 locations
DOuble SEquential External Defibrillation for Refractory VF

Despite significant advances in resuscitation efforts, there are some patients who remain in refractory ventricular fibrillation (VF) during out-of-hospital cardiac arrest. Double sequential external defibrillation (DSED) and vector change defibrillation have been proposed as viable options for patients in refractory VF. This cluster randomized trial will compare (1) continued resuscitation …

  • 0 views
  • 23 Jan, 2021
  • 4 locations
SI + CC Versus 3:1 C:V Ratio During Neonatal CPR

Research question In newborn infants requiring CPR, does CC superimposed by sustained inflation compared to 3:1 compression to ventilation ratio improves return of spontaneous circulation? Overall objective: CC superimposed by sustained inflation will improve short- and long-term outcomes in preterm (>28 weeks or older) and term newborns. Hypothesis to be …

  • 330 views
  • 24 Jan, 2021
  • 22 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

  • 0 views
  • 20 Feb, 2021
  • 1 location
Perineal Local Infiltration Study

The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The repair of such lacerations is usually done using a pre-existing epidural analgesia. Once the analgesic effect of the epidural analgesia fades, the laceration may cause intolerable pain, and result in emotional stress, difficulties in …

  • 7 views
  • 03 Mar, 2021
Dose Response of Epinephrine

Epinephrine is the principal physiologic defense against hypoglycemia in type 1 and longer duration type 2 DM. Despite this, it is unknown how epinephrine regulates in-vivo endothelial function

hypoglycemia
epinephrine
body mass index
  • 176 views
  • 25 Jan, 2021
  • 1 location
Bioavailability of Nasal Epinephrine

A Study to Compare the Bioavailability of Epinephrine following a Single Nasal Dose of FMXIN002 Microspheres Powder with Epinephrine 0.3 mg Intramuscular Injection in Adult Subjects with

  • 0 views
  • 31 Jan, 2021
  • 1 location
Effect of Epinephrine on Post-polypectomy Pain

Epinephrine is widely used in endoscopic mucosal resection of large polyps to prevent post-polypectomy bleeding. No previous studies looked at increase in immediate post-polypectomy pain with

mucosal resection
colorectal polyps
polypectomy
  • 0 views
  • 28 Jan, 2021
  • 1 location
Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies

Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will

bronchoscopy
epinephrine
lung transplant
  • 6 views
  • 25 Jan, 2021
  • 2 locations
DEpth of EPinephrine Delivery With Auto-injectors Devices

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Although there are several causes of fatal anaphylaxis, food allergy is one of the most common. Epinephrine

  • 19 views
  • 03 Feb, 2021
  • 1 location