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Found 100 clinical trials
The Efficacy of Local Infiltration Analgesia for Postoperative Pain Management After Total Knee Arthroplasty

This prospective, double-blinded, randomized controlled study evaluates the effects of peripheral nerve blocks with and without local infiltration analgesia for postoperative pain management after primary total knee arthroplasty. There are no any studies that show the demand for local infiltration analgesia when together peripheral nerve blocks are performed. Patients undergoing …

  • 27 Jan, 2021
  • 1 location
Paravertebral Block vs. General Anesthesia for Major Abdominal Surgery

Elderly patients are usually presented with higher risk for developing cardiopulmonary complications after general anesthesia (GA). Bilateral paravertebral block (PVB) has been associated with favorable outcomes in patients undergoing ventral hernia repair. Hence, elderly patients undergoing major abdominal surgery may benefit from PVB anesthetic technique.

  • 27 Jan, 2021
  • 1 location
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.

  • 23 Jan, 2021
  • 1 location
Intralesional 5-Fluorouracil (5FU) Topical Imiquimod Treatment for SCC

This clinical trial proposes to evaluate a relatively unexplored approach to treatment of squamous cell carcinoma (SCC) on the lower extremities. The strategy is to directly and specifically deliver drug to the tumor. For the proposed phase I clinical trial, the investigators will perform intralesional injections of a well characterized, …

  • 26 Jan, 2021
  • 1 location
Dexamethasone and the Prevention of Post-Extubation Airway Obstruction in Adults

Laryngotracheal injury related to intubation may cause narrowing of the airway due to edema of the glottis. Post-extubation airway frequently necessitating re-intubation and resulting in the prolongation of intensive care. Factors correlating with the development of post-extubation stridor include age, female gender, an elevated Acute Physiologic and Chronic Health Evaluation …

systolic blood pressure
oxygen saturation
  • 07 Nov, 2020
  • 1 location
Comparison of Postoperative Pain After Instrumentation in Different Visits With Different Single File Systems.

Comparison of Postoperative Pain after Root Canal preparation, in Single and Multiple Visits, with Reciprocating and Rotary Single-File Systems: A Randomized Clinical Trial. Aim:1. Compare between the postoperative pain after root canal preparation, in single and multiple visits. 2. To assess the influence of reciprocating and rotary single-file systems instrumentation …

  • 28 Feb, 2021
  • 1 location
Comparison of Anti-microbial Efficacy of Calcipex and Metapex in Endodontic Treatment of Chronic Apical Periodontitis

Introduction Pulpal necrosis may lead to spread of the infection from the pulp to involve the apex of the tooth and surrounding bone which when asymptomatic with periapical radiolucency on radiograph, is called chronic apical periodontitis. In order to eliminate the virulent bacteria and to overcome the inflammation in the …

  • 01 Feb, 2021
  • 1 location
Vasoactive Drugs in Intensive Care Unit

epinephrine. To investigate this hypothesis, the investigators are conducting a randomized double blind controlled trial comparing phenylephrine and vasopressin vs. norepinephrine and epinephrine in ICU

urine output
lactic acid
  • 26 Jan, 2021
  • 1 location
RCT of Gastric ESD With or Without Epineprhine Added Solution

This is an international multi-center randomised controlled study comparing outcomes of gastric endoscopic submucosal dissection (ESD) with or without addition of epinephrine in the submucosal

endoscopic submucosal dissection
  • 25 Jan, 2021
  • 7 locations
Oxytocin and Fetal Heart Rate Changes

The reported risk of nonreassuring fetal heart trace following neuraxial analgesia is 3-23%. This variability may be due to fluid and oxytocin management prior to and during the initiation of neuraxial analgesia. The study hypothesis is that decreasing the oxytocin infusion rate by 50 % prior to initiation of combined …

  • 24 Jan, 2021
  • 2 locations