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Found 56 clinical trials
Does the Use of Higher Versus Lower Oxygen Concentration Improve Neurodevelopmental Outcomes at 18-24 Months in Very Low Birthweight Infants - The HiLo-Trial (HiLo)

Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8 percent of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before 29 weeks' gestation. At this gestational age, the lungs are not fully developed and it is not …

  • 0 views
  • 21 Oct, 2022
  • 6 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

dementia
parkinson's disease
dopa
  • 8 views
  • 03 May, 2022
  • 1 location
Dose Response of Epinephrine (Epineprhine)

Epinephrine is the principal physiologic defense against hypoglycemia in type 1 and longer duration type 2 DM. Despite this, it is unknown how epinephrine regulates in-vivo endothelial function

Accepts healthy volunteers
hypoglycemia
body mass index
epinephrine
  • 176 views
  • 21 Apr, 2022
  • 1 location
The Effect of Epinephrine, Norepinephrine and Phenylephrine on Intraoperative Hemodynamic Performance - a Prospective Double-blinded Randomized Clinical Trial (RACE)

unknown. Therefore, the investigators evaluate the effect of intraoperative continuous infusion of epinephrine, norepinephrine and phenylephrine on intraoperative cardiac output. The investigators further

  • 0 views
  • 28 Oct, 2022
  • 1 location
Terlipressin for Refractory Septic Shock (TERESEP)

Norepinephrine was recommended as the first vasopressor for septic shock resuscitation. For the patient who did not response to high dose norepinephrine, epinephrine was recommended.

lactic acid
vasopressin
terlipressin
norepinephrine
resuscitation
  • 16 views
  • 04 Mar, 2022
  • 1 location
Alkalinization of Adrenalized Lidocaine in Extending Epidural Analgesia for Extremely Urgent Cesarean Section During Labor: a Randomized Controlled Trial. (QETAL)

Prospective randomized study comparing the use of lidocaine 2% with epinephrine buffered with sodium bicarbonate and lidocaine 2% with epinephrine as epidural top-up for extremely urgent

cesarean section
prenatal
  • 0 views
  • 18 Oct, 2022
  • 2 locations
Pecto-intercostal Fascial Block (PIFB) for Postop Analgesia Following Sternotomy in Cardiac Surgery Patients

epinephrine, clonidine, and dexamethasone will have lower dynamic pain over the first 36 hours compared to those receiving PIFB with just bupivacaine and epinephrine.

  • 0 views
  • 11 Apr, 2023
  • 1 location
Tumescence in HNC Skin Graft Reconstruction

blood loss during harvest of large skin grafts and excision of large burns when compared with the application of topical epinephrine as was the historic standard practice.4-6 Tumescence also creates a

Accepts healthy volunteers
  • 0 views
  • 25 Mar, 2022
  • 1 location
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)

reuptake inhibitors (SSRI's) such as Prozac has been demonstrated to increase basal epinephrine levels and enhance baroreflex control of Sympathetic nervous system (SNS) activity. What is unknown is

retinopathy
glycosylated hemoglobin
hemoglobin a1c
insulin resistance
sugars
  • 221 views
  • 27 Apr, 2022
  • 1 location
Postoperative Pain Control Using Local Wound Infiltration in Adolescent Idiopathic Surgery

injection of 0.25% bupivacaine with epinephrine or a placebo of equal volume injectable saline. Patient-reported outcomes will be collected at 1-, 6-, 12- and 24-months postoperatively.

bupivacaine
postoperative pain
acute pain
opioid
pain relieving
  • 0 views
  • 07 Oct, 2022
  • 1 location