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Found 50 clinical trials
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ACNS0831, Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years.

ACNS0831, Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years.

  • 66 views
  • 08 Nov, 2020
  • 1 location
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma

The overall aim of this project is to improve the outcome of patients diagnosed with ependymoma by improving and harmonising the staging and the standard of care of this patient population and

  • 53 views
  • 21 Oct, 2021
  • 64 locations
Combination Intraventricular Chemotherapy Pilot Study: 5-Azacytidine (5-AZA) and Trastuzumab Infusions Into the Fourth Ventricle or Resection Cavity in Children and Adults With Recurrent or Residual Posterior Fossa Ependymoma

patients with recurrent posterior fossa ependymoma and to assess the antitumor activity of simultaneous infusions of 5-Azacytidine and trastuzumab into the fourth ventricle of the brain or resection cavity

  • 0 views
  • 13 Aug, 2021
  • 1 location
Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT (MEMMAT)

Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation

ependymoma
medulloblastoma
combinations
bevacizumab
karnofsky performance status
  • 63 views
  • 23 Apr, 2022
  • 20 locations
Methionine PET/CT Studies In Patients With Cancer

The purpose of this study is to test the usefulness of imaging with radiolabeled methionine in the evaluation of children and young adults with tumor(s). Methionine is a naturally occurring essential amino acid. It is crucial for the formation of proteins. When labeled with carbon-11 (C-11), a radioactive isotope of …

positron emission tomography
MRI
nervous
fdg pet
essential amino acid
  • 53 views
  • 23 Jan, 2022
  • 1 location
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

erdafitinib
graft versus host disease
samotolisib
anti-cancer agents
interleukins
  • 1032 views
  • 01 Jul, 2022
  • 106 locations
LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

This phase I trial studies the side effects of linear energy transfer (LET) optimized image modulated proton therapy (IMPT) in treating pediatric patients with ependymoma. Radiation therapy such

tumor cells
ependymoma
  • 1 views
  • 03 Feb, 2022
  • 1 location
131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

assess the feasibility of incorporating cRIT 131I-omburtamab for patients with recurrent ependymoma. Direct intraventricular delivery of radiolabeled tumor-specific antibodies may aid in both the

  • 0 views
  • 25 Apr, 2022
  • 1 location
Feasibility Trial of Optune for Children With Recurrent or Progressive Supratentorial High-Grade Glioma and Ependymoma

This feasibility trial studies how well the Optune device works in treating younger patients with recurrent/refractory/progressive supratentorial malignant glioma and ependymoma. The TTFields

monoclonal antibodies
ependymoma
biological factors
malignant glioma
corticosteroids
  • 6 views
  • 25 Feb, 2022
  • 9 locations
Immunotherapy for Recurrent Ependymomas in Children Using Tumor Antigen Peptides With Imiquimod

ependymomas. Eligible patients are stratied by primary tumor location.

initial diagnosis
ependymoma
dexamethasone
corticosteroids
metastasis
  • 10 views
  • 22 Jan, 2022
  • 1 location