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Found 5 clinical trials
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

/velpatasvir (SOF/VEL, Epclusa), followed then by switch to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF, Biktarvy) for an additional 48 weeks.

hiv therapy
emtricitabine
velpatasvir
tenofovir
antiviral therapy
  • 67 views
  • 23 Jan, 2021
  • 1 location
Expanding the Pool in Orthotopic Heart Transplantation

This is an open-label, pilot trial to test the safety and efficacy of transplantation of hearts from HCV seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV Ab+/NAT+) donors to HCV seronegative recipients on the heart transplant waitlist. Treatment and prophylaxis will be administered, using a transmission-triggered approach for the …

hepatitis c antibody
velpatasvir
hepatitis b surface antigen
drug use
cirrhosis
  • 23 views
  • 27 Jan, 2021
  • 1 location
The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients

This is an open-label, pilot trial to test the safety and efficacy of transplantation of livers from Hepatitis C seropositive non-viremic (HCV Ab+/NAT-) and HCV seropositive viremic (HCV Ab+/NAT+) donors to HCV seronegative recipients on the liver transplant waitlist. Treatment and prophylaxis will be administered, using a transmission-triggered approach for …

immune globulin
liver transplant
hepatitis c antibody
velpatasvir
hepatitis
  • 1 views
  • 26 Jan, 2021
  • 1 location
Transplanting Hepatitis C Kidneys Into Negative Kidney Recipients

This study is being conducted to determine safety and effectiveness of transplanting kidneys from Hepatitis C-positive donors into Hepatitis C-negative patients on the kidney transplant waitlist, who will then be treated with the appropriate direct-acting antiviral (DAA) after the single kidney transplantation.

dialysis
kidney transplant
  • 0 views
  • 27 Jan, 2021
  • 1 location
Efficacy and Safety of Direct Anti HCV Drugs in the Treatment of SARS-COV-2 (COVID-19)

COVID 19 which started from a zoonotic transmission related to crowded markets was confirmed to have a high potential for transmission to close contacts on 20 January 2020 by the National Health Commission of China and it was announced as a pandemic by the WHO on 11 March 2020. There …

  • 0 views
  • 05 Mar, 2021
  • 1 location