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Found 29 clinical trials
We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury. (ELABELA(ELA))

an anticoagulant. The supernatant was removed and stored at -80°C, and the levels of plasma ELA (enzyme-linked immunosorbent assay) were measured using a standardized ELA kit. Additionally, serum

Accepts healthy volunteers
  • 30 Aug, 2023
Unstable Angina Pectoris in Comorbidity With Anxiety-depressive Syndrome

blood serum by enzyme-linked immunosorbent assay (ELISA). All participants in the study had blood drawn in the morning on fasting after 8-12 hours of fasting from the cubital vein. The level of

unstable angina
angina pectoris
stable angina
heart disease
  • 26 Jan, 2021
  • 1 location
Josef Ressel Centre Perinatal Programming (JRP)

Chromatography, Mass Spectrometry, Enzyme-Linked Immunosorbent Assay (ELISA) and more. Also questionnaires for the evaluation of the maternal milk feeding style are used as well as the Baby and Child Eating and

Accepts healthy volunteers
metabolic syndrome
  • 17 Sep, 2023
  • 1 location
The Role of Histamine in Breast Cancer Bone Pain

This trial studies histamine and bone pain association in participants with breast cancer that has spread to the bone. Studying histamine levels in samples of blood from participants with breast cancer in the laboratory may help doctors learn more about reducing cancer bone pain and preventing further bone metastasis.

  • 16 Oct, 2022
  • 1 location
Blood Brain Barrier Dysfunction and Postoperative Neurocognitive Disorders (BBBSx)

Postoperative neurocognitive disorders (PND), which include postoperative delirium and both acute and longlasting neurocognitive deficits, are a significant public health problem, leading to a cascade of deleterious complications. Older adults are particularly at-risk of developing PND both in the short and long term. Although age is consistently reported as an …

  • 20 Aug, 2023
  • 1 location
Presence of Toxins From Smoking in the Follicular Fluid of Women Undergoing Intracytoplasmic Sperm Injection Treatment

Smoking is associated with many adverse health effects like circulatory disorders, pulmonary diseases or heart diseases. It was also shown that smoking correlates with a significantly higher risk for miscarriage, preterm birth or a significantly decreased implantation rate or life birth rate, thus affects the chance to have children. Combustion …

intracytoplasmic sperm injection
preterm delivery
Accepts healthy volunteers
  • 22 Aug, 2023
  • 1 location
Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

Background Influenza (flu) vaccinations are required for all NIH staff members who have direct contact with patients. SARS-CoV-2 vaccines are available to NIH staff. These vaccines are shown to be effective. Researchers want to learn about immunity in NIH staff members who get a flu and/or SARS-CoV-2 vaccine. Objective To …

Accepts healthy volunteers
influenza vaccination
hemagglutination inhibition
  • 04 Oct, 2022
  • 1 location
Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance

Hypothesis: SLE and RA increase risk of myocardial infarction (MI, heart attack). Immune reactants in the circulation of SLE patients downregulate cholesterol efflux proteins 27-hydroxylase and ABCA1 and upregulate scavenger receptor CD36, thus encouraging cholesterol accumulation. Adenosine A2A receptor agonist or statin treatment of cells exposed to SLE plasma (or …

psoriatic arthritis
Accepts healthy volunteers
  • 10 Apr, 2023
  • 1 location
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly (SmartAge)

Cognitive disorders increase with age and in the presence of metabolic diseases such as Type 2 Diabetes Mellitus (T2DM). In addition, digestive disorders, changes in dietary pattern and decreased activity negatively influence the microbiome. The hypothesis is that pharmacological intervention with metformin will modify the composition of the gut microbiota …

continuous glucose monitoring
type 2 diabetes mellitus
  • 04 Oct, 2022
  • 1 location