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Found 42 clinical trials
Effects of Angiotensin Converting Enzyme Inhibitors on Patency of Arterio-Venous Fistulas: A Randomized Controlled Trial

Chronic kidney disease (CKD) is one of the leading health problems imbibing a major portion of health budget worldwide. The global prevalence of CKD is estimated to be 13.4% with approximately 5 to 7 million people needing renal replacement therapy. There is lack of epidemiological surveys regarding CKD but it …

  • 0 views
  • 02 Dec, 2021
  • 1 location
Management of Angiotensin Inhibitors During the Perioperative Period (AIPOP)

This is a multicenter randomized clinical trial to determine the effect of continuation versus withdrawal of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers

postoperative complication
hypertension
  • 0 views
  • 22 Mar, 2022
  • 6 locations
The COVID-RASi Trial (COVID-19)

-risk for cardiovascular disease. The purpose of this study is to determine if renin-angiotensin system inhibitors (RASi), with angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor

myocardial infarction
diabetes
hypertension
potassium
infarct
  • 5 views
  • 26 Jun, 2021
  • 17 locations
Randomized Evaluation of Beta Blocker and Angiotensin Converting Enzyme Inhibitor (ACEI) /Angiotensin Receptor Blocker (ARB) Treatment in MINOCA Patients. (MINOCA-BAT)

randomized clinical trial is to determine whether oral beta-blockade compared to no oral beta-blockade, and whether Angiotensin Converting Enzyme Inhibitors (ACEI/ Angiotensin Receptor Blockers (ARB

  • 6 views
  • 17 Sep, 2022
  • 26 locations
CYCLONE 3: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Abemaciclib in Combination With Abiraterone Plus Prednisone in Men With High-Risk Metastatic Hormone-Sensitive Prostate Cancer (CYCLONE 3)

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse. Participation may last approximately 60 months.

cancer
adenocarcinoma
bone metastases
  • 0 views
  • 16 Sep, 2022
  • 101 locations
A 6-month Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and PK/PD of an age-and Body Weight-adjusted Oral Finerenone Regimen, in Addition to an ACEI or ARB, for the Treatment of Children, 6 Months to <18 Years of Age, With Chronic Kidney Disease and Proteinuria (FIONA)

and/or proteinuria. These include "angiotensin-converting enzyme inhibitors" (ACEI) and "angiotensin receptor blockers" (ARB). Both ACEI and ARB can improve kidney function by helping the renin

angiotensin ii receptor antagonists
angiotensin
hypertension
aldosterone
renin
  • 0 views
  • 20 Sep, 2022
  • 23 locations
The GUARDIAN Trial

The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP 85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward systolic pressure 110 mmHg (tight pressure management); or, 2) routine intraoperative blood pressure management and prompt resumption of chronic antihypertensive medications (routine pressure management).

  • 0 views
  • 28 Aug, 2021
  • 3 locations
Pentoxifylline in Diabetic Kidney Disease (PTXRx)

Pentoxifylline (PTX) is a medication that has been on the market since 1984 for use in disease in the blood vessels of the legs. There is some preliminary information that it may protect the kidneys from damage due to diabetes and other diseases. "Pentoxifylline in Diabetic Kidney Disease" is a …

diabetes
diabetic nephropathy
pentoxifylline
nephropathy
  • 42 views
  • 20 Jun, 2022
  • 16 locations
The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients

Objective propose: to investigate the effect of Ramipril in suppressing ST2 (suppression of tumorigenicity 2) in the cardiac mitral valve in patients with Rheumatic Heart Disease. We hypothesized that we hypothesized that ramipril will improve rheumatic mitral valve fibrosis through the downregulation of ST2.

heart disease
tricuspid valve repair
stenosis
rheumatic heart disease
mitral valve replacement
  • 116 views
  • 10 Feb, 2022
  • 1 location
Effect of RAS Blockers on CKD Progression in Elderly Patients With Non Proteinuric Nephropathies (PROERCAN01)

patients will receive angiotensin converting enzyme inhibitors, while the other half will not receive them. Renal function, proteinuria and cardiovascular events will be follow up during a three year

angiotensin
angiotensin converting enzyme
renin
ace inhibitor
proteinuria
  • 24 views
  • 23 Jan, 2021
  • 1 location