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Found 31 clinical trials
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MBB102073: A clinical research study for subjects with Diabetes Mellitus, Type 2.

MBB102073: A clinical research study for subjects with Diabetes Mellitus, Type 2.

  • 28 views
  • 08 Nov, 2020
  • 1 location
featured
Clinical Trial to evaluate the safety and efficacy of a new medication in patients with Type II Diabetes with Inadequately Controlled Hypertension.

Clinical Trial to evaluate the safety and efficacy of a new medication in patients with Type II Diabetes with Inadequately Controlled Hypertension.

  • 230 views
  • 08 Nov, 2020
  • 1 location
Anakinra Versus Placebo for the Treatment of Acute MyocarditIS

> Hypothesis : ANAKINRA in addition to standard therapy for treatment of Acute Myocarditis is superior to standard therapy based on an association of beta-blockers and Angiotensin-Converting-Enzyme

  • 1 views
  • 27 Jan, 2021
  • 3 locations
Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

The combination treatment of protein kinase B (AKT) inhibitor, afuresertib, with androgen synthesis enzyme inhibitor, LAE001, may provide an effective treatment for metastatic castration

gilbert's syndrome
AKT
antiandrogen therapy
apalutamide
renal function
  • 55 views
  • 29 Mar, 2021
  • 14 locations
Safety Tolerability and Efficacy of Nidufexor in Patients With Diabetic Nephropathy

care (angiotensin converting enzyme inhibitor or angiotensin receptor blocker). This non-confirmatory Phase 2 study is designed to determine the safety, tolerability, efficacy, pharmacokinetics and

enzyme inhibitors
type 2 diabetes mellitus
angiotensin
diabetes
nephropathy
  • 66 views
  • 25 Apr, 2021
  • 23 locations
Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment: Testing Alternative Antihypertensive Regimens Using ACE-Inhibitors Calcium Channel Blockers and Diuretics (LIGHT-ACD)

This trial aims to compare the efficacy of several guideline-based hypertensive medication regimens initiated with Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker [A

antihypertensive drugs
calcium
calcium channel blockers
hypertension
angiotensin
  • 0 views
  • 25 Apr, 2021
  • 3 locations
Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

The main objective of this study is to evaluate the efficacy of SZC as compared with placebo in keeping potassium levels within the normal range (3.5-5.0 mEq/L) while on spironolactone 25 mg daily without assistance of rescue therapy for hyperkalaemia (HK).

  • 0 views
  • 24 May, 2021
  • 37 locations
Atrasentan in Patients With IgA Nephropathy

The ALIGN Study is a phase 3, double-blind, placebo-controlled study to compare the efficacy and safety of atrasentan to placebo in patients with IgA nephropathy (IgAN) at risk of progressive loss of renal function.

renal function
nephropathy
  • 0 views
  • 28 Jul, 2021
  • 35 locations
Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy

The overall aim of this project is to establish potential benefits of a novel lifestyle (physical activity and dietary nitrate) and pharmacological (angiotensin receptor neprilysin inhibitor) interventions in patients with hypertrophic cardiomyopathy (HCM). HCM is the most common genetic cardiovascular disease with a broad spectrum of disease severity. Angiotensin receptor …

heart failure
hypertrophic obstructive cardiomyopathy
hypertrophy
vasodilatation
neprilysin inhibitor
  • 0 views
  • 24 Jan, 2021
  • 5 locations
Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema

Angiotensin Converting Enzyme (ACE) inhibitors are among the most important and widely prescribed drugs. They reduce the morbidity and mortality associated with high blood pressure, heart disease, and kidney disease. Unfortunately, their use carries the risk of causing life-threatening airway swelling in some patients. There is currently no treatment for …

  • 0 views
  • 27 Jan, 2021
  • 1 location