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Found 1727 clinical trials
Combination of Baricitinib and Adalimumab in Rheumatoid Arthritis (CRI-RA)

combination of targeted therapies have been published, suggesting a certain efficacy in patients with refractory RA. The first ones focused on inflammatory bowel diseases and psoriasis, but more recently

rheumatism
prednisone
antirheumatics
tumour necrosis
adalimumab
  • 0 views
  • 15 Mar, 2022
  • 6 locations
Diet Intervention Treatment for Active Ulcerative Colitis

The purpose of this study is to determine if a sustainable non-elemental diet can be used as a probiotic tool to alter the dysbiotic microbiome found in individuals with ulcerative colitis and thereby decrease disease activity.

medical therapy
  • 0 views
  • 25 May, 2021
  • 1 location
GM-CSF Fosfomycin and Metronidazole for Pouchitis in Ulcerative Colitis Patients After Restorative IPAA Surgery

This study will examine whether the application of GM-CSF, fosfomycin and metronidazole locally in the pouch is safe and effective in the treatment of pouchitis for patients with ulcerative colitis, and whether treatment changes the microbiome of the pouch.

  • 0 views
  • 20 Sep, 2021
  • 1 location
Video Coaching of Physical Activity in Axial Spondyloarthritis (SatiSpAction)

The primary objective of the study is to demonstrate the beneficial effect of a 3 months home-based physical exercise program supervised by online videos, in addition to the usual recommendations, in comparison with usual physical activity as recommended by the WHO. The secondary objectives of the study are : to …

  • 0 views
  • 13 Mar, 2022
Anti-inflammatory Actions of Osteopathic Manipulative Treatment (OMT_taVNS)

This study evaluates the hypothesis that osteopathic manipulative treatment (OMT) and non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) elicit anti-inflammatory actions through activation of the parasympathetic nervous system. In a cross-over design, research participants will be subjected to various combinations of OMT, taVNS, or sham interventions during four study sessions, …

Accepts healthy volunteers
electrocardiogram
  • 171 views
  • 23 Mar, 2022
  • 1 location
Sacral Nerve Stimulation for Mild-to-Moderate or Refractory Rheumatoid Arthritis

This pilot study will assess the efficacy of sacral never stimulation (SNS) for the treatment of adult patients with active, mild-to-moderate rheumatoid arthritis or those with refractory disease. The study will enroll 60 subjects in a single center. All eligible subjects will be randomly divided into two groups at a …

Accepts healthy volunteers
antirheumatics
  • 0 views
  • 13 Mar, 2022
  • 1 location
FMT in Initial CDI (FinCDI)

The study explores fecal microbiota transfer via retention enema after the first clostridioides difficile episode.

  • 0 views
  • 11 Mar, 2022
  • 1 location
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture (MICROBONE)

Gut microbiota regulate metabolism of their human host. Some diseases are associated with variations in gut microbiota diversity and higher fracture risk. Intestinal bacteria synthesize or influence synthesis of factors modulating bone metabolism. The link between gut microbiota and bone was assessed mainly in experimental animal studies. Clinical data, e.g. …

postmenopausal osteoporosis
bone densitometry
bone mineral density
quantitative computed tomography
spinal fracture
  • 227 views
  • 26 Feb, 2022
  • 1 location
Fecal Microbial Transplantation for Ileal Pouch Anal Anastomosis Patients

The investigator is hypothesize that an intensive FMT regimen will have superior efficacy the treatment of inflammatory disorders of the pouch (pouchitis and CLDP).

  • 0 views
  • 03 Mar, 2022
  • 1 location
Healthy Volunteer Short Chain Fatty Acid Study

The purpose of this study is to evaluate the production of short chain fatty acids (fatty acids are part of your diet) in stool through the measurement of fecal inulin after a one-time ingestion of 10-gram dose of inulin among healthy adult volunteers.

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location