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Found 93 clinical trials
Quality Assessment of Orotracheal Intubation Without Neuromuscular Blocking Agents in Obese Patients (OBEREM)

This study will assess the condition of orotracheal intubation in obese patients undergoing an elective bariatric surgery without the use of neuromuscular blocking agents. During the induction of general anesthesia, Propofol - Remifentanil combination will be used. The patients will be randomized in 2 groups with different doses of Remifentanil.

bariatric surgery
  • 0 views
  • 19 Jun, 2022
  • 1 location
A Multicenter, Randomized, Double-blinded, Propofol-controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of HSK3486 Injectable Emulsion for Induction of General Anesthesia in Adults Undergoing Elective Surgery

To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous [IV] slow injection over 30 [±5] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection over 30 [±5] seconds for first dose, an additional 1.0 mg/kg if needed) in …

Accepts healthy volunteers
  • 0 views
  • 21 Oct, 2022
  • 6 locations
Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery

Perioperative pulmonary complications such as atelectasis, hypoxemia, and pneumonia after ventilatory management during general anesthesia have a negative impact on patient outcomes. The possibility of reducing perioperative pulmonary complications by lung recruitment, which uses positive pressure to prevent alveolar collapse, has been reported. Although laparoscopic surgery, which has been widely …

  • 0 views
  • 05 Sep, 2021
  • 1 location
Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

The purpose of this study is to determine whether deep neuromuscular blockade provides better surgical conditions than moderate neuromuscular blockade in patients undergoing vocal cord resections requiring jet ventilation.

  • 4 views
  • 27 Apr, 2022
  • 1 location
Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery

Arthroscopic knee surgery is a minimally invasive operation. Postoperative pain usually occurs, especially within 24 hours after surgery, the incidence of pain can be more than 76%. Pain will affect the patient's emotions and life, cause adverse effects, and even lead to postoperative delirium. This study aimed to investigate the …

  • 0 views
  • 05 May, 2022
  • 1 location
Ultrasound-guided H-FICB for Arthroscopic Knee Surgery: What is the Optimal Dose of Dexmedetomidine?

Total knee replacement (TKR) is among the most commonly performed orthopedic procedures, and a six-fold increase in the number of TKR cases world-wide is projected within a decade as the aging of the populations . As the number of the TKR procedures increases, various approaches increasing the satisfaction and comfort …

  • 0 views
  • 07 Oct, 2022
  • 1 location
Doxapram Therapy in Preterm Infants (DOXA Trial)

Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system. AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, …

continuous positive airway pressure
assisted ventilation
mechanical ventilation
pulmonary disease
  • 0 views
  • 12 Jul, 2022
  • 15 locations
Lidocaine And Neuromonitoring in Thyroid Surgery

The aim of this study is to test the hypothesis that the quality of recovery with topical lidocaine is better than placebo.

intubation
lidocaine
  • 0 views
  • 07 Oct, 2022
  • 1 location
Silk Protein Microparticle-based Filler for Injection Augmentation

This study will investigate the safety and efficacy of a silk protein microparticle-based filler for vocal fold injection augmentation to treat dysphonia/dysphagia secondary to vocal fold paralysis. Participants will receive one injection and follow-up for a planned period of 12 months.

  • 0 views
  • 18 Dec, 2021
  • 1 location
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty

Adding a single preoperative dose of gabapentin to the standard pain regimen will reduce postoperative opioid consumption within the first 72 hours in patients undergoing rhinoplasty.

  • 0 views
  • 29 Sep, 2021
  • 1 location