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Found 178 clinical trials
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans

: To determine if prolonged (3-month) treatment with galantamine improves endothelial dysfunction as measured by vascular reactivity in AAs. The investigators will measure vascular reactivity in

Accepts healthy volunteers
  • 0 views
  • 02 Jan, 2022
  • 2 locations
Artery Function Responses to Heat Therapy and Exercise Training

This study will explore the effects of 8 weeks of local leg heat therapy, exercise training, or both on measures of vascular function, cardiorespiratory fitness, and muscle strength in young, healthy individuals. Participants will be allocated into either a control group that will maintain their regular physical activity habits; or …

  • 1 views
  • 02 Aug, 2021
  • 1 location
Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19

antioxidant protein glutathione (GSH), elevated oxidative stress, inflammation, impaired mitochondrial function, immune dysfunction, and endothelial dysfunction. It is known and established that GSH

  • 1 views
  • 25 Mar, 2022
  • 1 location
Exercise Training and Endothelial Function in Type 1 Diabetes

Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the

  • 0 views
  • 26 Jan, 2021
  • 1 location
Re-Energize Fontan

that Fontan patients have poor exercise capacity, associated with a greater risk of morbidity and mortality, in addition to decreased muscle mass, abnormal muscle function, and endothelial dysfunction

  • 0 views
  • 19 Mar, 2021
  • 1 location
Melatonin and Salt on Blood Vessel Function

Increased dietary sodium causes increases in oxidative stress and damages blood vessels. Americans eat more than the recommended amount of sodium. Melatonin is a powerful endogenous antioxidant that has reduced oxidative stress levels in clinical and healthy populations. This study will investigate whether melatonin can attenuate the negative effects of …

antioxidants
Accepts healthy volunteers
  • 0 views
  • 02 Mar, 2022
  • 1 location
Comparison of Lower-risk MDS Patients With and Without Improvements in Fatigue Following Blood Transfusion Therapy (FITME)

At present, it is unclear why some myelodysplastic patients (MDS) receiving blood transfusion therapy exhibit an increase in Hemoglobin (Hb) without a concurrent improvement in fatigue. Research is thus required to elucidate on why fatigue persists in some MDS patients in order to devise strategies to alleviate fatigue in "non-responders" …

  • 0 views
  • 22 Mar, 2022
  • 1 location
Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans

Americans continue to consume high amounts of sodium. Potassium is notable for its blood pressure lowering effects but less is known regarding its effect on the vasculature. This investigation seeks to determine the role of dietary potassium on the vasculature in the presence of a high sodium diet in salt-resistant …

potassium
Accepts healthy volunteers
  • 0 views
  • 02 Mar, 2022
  • 1 location
Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities

A single-center, open, prospective, randomized, controlled clinical trial will include 120 patients with lower limb lymphedema who undergo treatment in an office-based vascular lab at the Ryazan regional clinical cardiology dispensary, Ryazan, Russia. The patients will be recruited by the staff of the Department of cardiovascular, endovascular, operative surgery, and …

  • 32 views
  • 13 Jun, 2021
  • 1 location
Far Infrared Therapy on Arteriovenous Fistulas in Hemodialysis Patients

The number of hemodialysis patients in the world are increasing. In order to receive a sufficient dialysis, the patients needs a well functioning and stable vascular access - preferably an arteriovenous fistula (AVF). Unfortunately, the AVF has a high incidence of stenosis with percutaneous trans luminal angioplasty (PTA) as the …

dialysis
chronic hemodialysis
stenosis
  • 0 views
  • 25 Jan, 2021
  • 9 locations