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Found 138 clinical trials
Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema (COMPLETE-1)

The purpose of this protocol is to perform a pilot prospective randomized controlled clinical trial to evaluate the potential role of lung fissure completion strategy (experimental intervention) in addition to endobronchial valve (EBV) placement (representing "standard-of-care") in select patients with severe COPD/emphysema and with evidence for <95% fissure completion between …

  • 0 views
  • 05 Jul, 2022
  • 1 location
Effectiveness of Rotating System and Single File Reciprocating System in Temporal Molars

Is an in vivo study to test the effectiveness of the reciprocating system Reciproc blue and the rotating system VDW.ROTATE in primary molars.

Accepts healthy volunteers
  • 0 views
  • 03 Jun, 2022
  • 1 location
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction (SAVED-1)

The purpose of this protocol is to perform a pilot prospective controlled clinical trial to evaluate the potential role of lung fissure completion with pleural adhesiolysis strategy (experimental intervention) in severe emphysema/COPD patients with failed bronchoscopic lung volume reduction (BLVR) via the use of endobronchial valves (EBVs) therapy. In select …

  • 0 views
  • 30 Jun, 2022
  • 1 location
Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis (PREGnant)

A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate. The investigators' central

fibroids
embryo transfer
cavity
adenomyosis
infertility
  • 52 views
  • 04 Oct, 2022
  • 5 locations
A Phase 3b Study to Evaluate the Safety and Efficacy of Elagolix in Combination With Combined Oral Contraceptives in Premenopausal Women With Documented Endometriosis and Associated Moderate to Severe Pain

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relationships, sexuality and sexual activity, and

combined oral contraceptives
endometriosis
dysmenorrhea
elagolix
  • 1355 views
  • 28 Oct, 2022
  • 119 locations
TUC3PII-01_TU2670 Phase IIa Clinical Study

This Protocol for TU2670 is to investigate the efficacy, safety, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple doses of TU2670 in subjects with moderate to severe endometriosis

endometriosis
  • 10 views
  • 10 Dec, 2021
  • 40 locations
  • 117 views
  • 21 Oct, 2022
  • 74 locations
MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer

This research study is designed to determine if targeted Magnetic Resonance Imaging (MRI) Ultrasound (US) fusion biopsy is better than the standard of care ultrasound guided biopsy alone in diagnosing subjects with clinically significant prostate cancer with MRI visible lesions. This study will consist of comparing the standard of care …

  • 2 views
  • 22 Mar, 2022
  • 3 locations
Sentinel Node Biopsy in Endometrial Cancer (ENDO-3)

Endometrial cancer (EC) is the most common gynaecological cancer. Current treatment of EC typically includes removal of the uterus and to determine the extent of the disease (removal of fallopian tubes, ovaries & if required a lymph node dissection (surgical staging)). While lymph node dissection may be valuable to guide …

  • 0 views
  • 07 Oct, 2022
  • 5 locations
Conservative Endometrioma Surgery (BLAST)

To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation. The 2 conservatives techniques used are: The

infertility
cyst
anti-mullerian hormone
endometrioma
  • 13 views
  • 13 Jul, 2022
  • 4 locations