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Found 9 clinical trials
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IGFBP-3 in Ovarian Cancer Invasion

An ovarian cancer cell line (OVTW-59) derived from an ovarian endometrioid carcinoma was established and its sublines, labeled as P0, P1, P2, P3, and P4 with increasing invasion abilities

cancer
carcinoma
adenocarcinoma
endometrioid carcinoma
ovarian cancer
  • 1 views
  • 07 Nov, 2020
  • 1 location
None
MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO)

The purpose of this study is to evaluate the efficacy of addition of letrozole to the standard maintenance therapy in subjects following a primary diagnosis of Estrogen-receptor (ER) positive high and low grade epithelial ovarian cancer (including fallopian tube and primary peritoneal cancer) and subsequent primary treatment surgery and chemotherapy. …

cancer chemotherapy
peritoneal cancer
letrozole
ovarian cancer
ovarian epithelial carcinoma
  • 0 views
  • 24 Sep, 2021
  • 20 locations
None
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This trial enrolls participants for …

primary tumor
human immunodeficiency virus
neuroendocrine carcinoma
carcinoid
pancreatic adenocarcinoma
  • 6055 views
  • 02 Dec, 2021
  • 820 locations
None
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer

This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky. Detection of ovarian malignancy often occurs subsequent to the initial transvaginal sonography (TVS) screen therefore, it is important to offer continued screening to study participants based on our …

breast cancer
cancer of the ovary
  • 0 views
  • 27 Jul, 2021
  • 1 location
None
Study of STRO-002 an Anti-Folate Receptor Alpha (FolR ) Antibody Drug Conjugate in Ovarian & Endometrial Cancers

Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-002 given intravenously every 3 weeks.

cancer chemotherapy
undifferentiated carcinoma
cancer
peritoneal cancer
measurable disease
  • 87 views
  • 19 Nov, 2021
  • 25 locations
None
Testing the Combination of Olaparib and Durvalumab Cediranib and Durvalumab Olaparib and Capivasertib and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone and Olaparib Alone

This phase II trial studies the effects of the combination of olaparib and durvalumab, cediranib and durvalumab, olaparib and capivasertib, and cediranib alone in treating patients with endometrial cancer that has come back (recurrent) or does not respond to treatment (refractory). Olaparib, cediranib, and capivasertib may stop the growth of …

cancer chemotherapy
luteinizing hormone
carcinoma
neutrophil count
serum pregnancy test
  • 81 views
  • 03 Dec, 2021
  • 505 locations
None
Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus.

Advanced technology has enabled radiation oncologists to more accurately and precisely target radiation to areas at risk while maximally sparing healthy tissue. Furthermore, there is growing evidence demonstrating both safety and efficacy for SBRT. We propose that these advantages are translatable to the adjuvant treatment of endometrial cancer. We submit …

cancer chemotherapy
cancer
immunomodulators
carcinoma
uterine disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FR )

This study, ELU- FR-1, is focused on adult subjects who have advanced, recurrent or refractory folate receptor alpha (FR) overexpressing tumors considered to be topoisomerase 1 inhibitor-sensitive based on scientific literature, and, in the opinion of the Investigator, have no other meaningful life-prolonging therapy options available. ELU001 is a new …

cancer
measurable disease
ovarian cancer
folic acid
triple negative breast cancer
  • 0 views
  • 24 Nov, 2021
  • 2 locations
None
Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

This study is being done to find out how often endometrial cancer recurs after the standard treatment as well as how often the standard treatment results in a lymphedema.

hysterectomy
endometrioid carcinoma
cancer
adenocarcinoma
  • 1 views
  • 11 Aug, 2021
  • 24 locations