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Found 273 clinical trials
Endometrial Cancer Lymphadenectomy Trial (ECLAT)

endometrial cancer (EC) FIGO Stages I or II and high risk of recurrence. Secondary aims will be to evaluate the effect of LNE on disease free survival (DFS) and quality of life, as well as the complications

  • 30 views
  • 29 Apr, 2022
  • 59 locations
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

Endometrial cancer is the most common gynecological malignancy affecting women's health. About 15% of the patients will have local late disease (stage III) with high risk of recurrence and tumor

adenocarcinoma
carcinoma
cancer
platelet count
endometrial adenocarcinoma
  • 0 views
  • 24 Jan, 2021
  • 1 location
PROfiling Based Endometrial Cancer Adjuvant Therapy (PROBEAT)

This is a prospective, multicenter, randomized phase III trial among women with endometrioid adenocarcinoma with high-intermediate and intermediate risk features to investigate the role of integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular features as …

  • 0 views
  • 10 May, 2022
  • 1 location
Sentinel Node Biopsy in Endometrial Cancer (ENDO-3)

Endometrial cancer (EC) is the most common gynaecological cancer. Current treatment of EC typically includes removal of the uterus and to determine the extent of the disease (removal of

  • 0 views
  • 07 Oct, 2022
  • 5 locations
Randomized Comparison Between Sentinel Lymph Node Biopsy and Lymph Node Dissection in Early Stage Endometrial Cancer (SELYE)

Through this clinical trial, the investigators aim to verify the usefulness and stability of sentinel lymph node mapping in endometrial cancer of clinical stage I-II.

adenocarcinoma
uterine disease
hysterectomy
carcinosarcoma
cancer
  • 0 views
  • 12 Mar, 2022
  • 1 location
PORTEC-4a: Molecular Profile-based Versus Standard Adjuvant Radiotherapy in Endometrial Cancer (PORTEC-4a)

This is prospective, multicenter, randomised phase III trial among women with endometrial cancer with high-intermediate risk features to investigate the role of an integrated clinicopathological

  • 77 views
  • 01 Mar, 2022
  • 30 locations
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features: the p53abn-RED Trial, the MMRd-GREEN Trial, the NSMP-ORANGE Trial and the POLEmut-BLUE Trial (RAINBO)

The RAINBO umbrella program consists of four clinical trials investigating new adjuvant therapies in endometrial cancer patients. Eligible patients will be assigned to one of the four RAINBO

durvalumab
carboplatin
paclitaxel
megestrol
cancer
  • 0 views
  • 24 Oct, 2022
  • 2 locations
Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus

Aim To investigate the effect of sentinel lymph node (SLN) sampling on the prognosis of patients with middle-high risk endometrial cancer obviously confined to the uterus before surgery.

  • 0 views
  • 09 Apr, 2022
  • 1 location
Biomarker Guided Treatment in Gynaecological Cancer

endometrial cancer. Predominantly, but not exclusively, such biomarkers have shown to be interesting in retrospective analysis of our large prospectively collected MoMaTEC1 series. Part 1: Performance

paclitaxel
cancer
ovarian cancer
lymphadenectomy
  • 45 views
  • 21 Jan, 2021
  • 8 locations
  • 112 views
  • 25 Oct, 2022
  • 19 locations