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Found 273 clinical trials
European Collaborative Multicenter Observational Study: Modular Treatment With PMMR and Targeted Compartmental Pelvic Lymphadenectomy Followed by Therapeutic Pelvic and Paraaortic Lymphadenectomy in Node Positive Disease for Locoregional Control in Endometrial Cancer FIGO Stages I-III

Intermediate/high risk endometrial cancer shows locoregional recurrence rates up to 20%. Also in so called low-risk disease 5-10% incidence of nodal metastasis is reported. Although adjuvant

cancer
adjuvant chemotherapy
carcinoma
metastasis
lymphadenectomy
  • 0 views
  • 25 Jan, 2021
  • 1 location
Preservation of Ovaries in Endometrial Malignancies: GYN POEM Trial

The purpose of this study is to learn more about the factors that influence decision-making before surgery (distress about cancer and/or reproductive concerns) and the possibility of regret after surgery.

cancer
surgery for endometrial cancer
uterine disease
  • 0 views
  • 25 Oct, 2022
  • 7 locations
Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in High-Risk Endometrial Cancers

cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help

carcinosarcoma
  • 0 views
  • 04 Oct, 2022
  • 1 location
Phenotypic Spectrum of CTCs in Tumors of the Female Reproductive System (CTCs)

patients with tumors of the female reproductive system (breast cancer, endometrial cancer, and ovarian cancer). The primary objective are: To assess the presence and number of

laparoscopy
Accepts healthy volunteers
cancer chemotherapy
ovarian cancer
cancer
  • 0 views
  • 11 May, 2022
  • 1 location
Endometrial Stromal Tumors: an Observational Study (EST)

Observational, retrospective and prospective study on Endometrial Stromal Tumor (EST)

stromal tumor
cancer chemotherapy
  • 24 views
  • 10 Oct, 2022
  • 1 location
Comparison of Toxicities Between Proton Therapy and IMRT for Post Operative Treatment of Endometrial or Cervical Cancers.

This trial is designed as a non-randomized pilot trial to study, in a preliminary fashion, whether proton radiation therapy (proton RT) reduces acute gastrointestinal toxicities at the end of treatment compared to intensity modulated radiation therapy (IMRT)

  • 0 views
  • 15 Feb, 2021
  • 1 location
Longitudinal Evaluation of Women Undergoing Pelvic Exenteration for Treatment of Gynecologic Malignancy

The study investigates whether certain characteristics of gynecological cancer can help researchers predict how well a patient recovers from surgery to remove the lower colon, rectum, and bladder, and create openings through which urine and stool are passed out of the body (pelvic exenteration). Comparing the types of surgery completed …

cancer
primary cancer
carcinoma
vaginal carcinoma
gynecologic cancer
  • 33 views
  • 16 Oct, 2022
  • 1 location
Effect of Pelvic Radiotherapy on the Intestinal Microbiome and Metabolome

Eight in ten patients will develop bowel problems during radiotherapy, eg diarrhoea, pain and incontinence, half will develop difficult long-term bowel problems. It is not known why some people get bowel problems and others do not and there is no test to predict who will develop bowel problems following their …

bladder tumor
cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

pathologic examination
immunomodulator
lymphadenectomy
cervical cancer stage
tumor cells
  • 27 views
  • 04 Oct, 2022
  • 1 location
Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives

This trial collects information about factors that affect communication of genetic test results, decision-making, and access to genetic testing in women with hereditary gynecological cancers. Studying individuals who are positive for a genetic mutation and immediate biological family members (including a parent, full-sibling, or child) may help identify cancer genes …

CHEK2
PTEN
Accepts healthy volunteers
hnpcc
LKB1
  • 46 views
  • 15 Jul, 2022
  • 1 location