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Found 273 clinical trials
Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

acetate (MA/MPA) alone as fertility-sparing treatment for patients with early endometrial carcinoma.

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
A Phase II Trial of Pembrolizumab Plus Olaparib for the Treatment of Patients With Persistent/Recurrent Endometrial Cancers

The purpose of this study is to find out whether the combination of pembrolizumab and olaparib is an effective treatment for people with persistent or recurrent endometrial cancer or endometrial

  • 13 Oct, 2022
  • 3 locations
A Phase II Clinical Trial Evaluating the Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy ± Anlotinib Hydrochloride Capsules for First-line Treatment of Patient With Advanced Endometrial Cancer

endometrial cancer, and explore biomarkers related to efficacy, mechanism of action, safety and/or pathological mechanisms. ORR is the primary endpoint.

  • 12 Oct, 2022
  • 4 locations
  • 07 Oct, 2022
  • 1 location
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

increased risk for infertility, metabolic syndrome, and type 2 diabetes mellitus, and possibly for cardiovascular disease and endometrial carcinoma. Polycystic ovary syndrome is diagnosed in adolescents

cardiovascular disease
endometrial carcinoma
  • 26 May, 2022
  • 1 location
Safety of Oral Micronized Progesterone Versus Norethisterone Acetate in Continuous Combination With Oral Estrogen as Menopausal Hormone Therapy - a Double-blind Randomized Study- PROBES Study (Progesterone Breast Endometrial Safety Study)

risk of endometrial cancer than by standard MHT. In a randomized trial, the balance between benefits and risks of mP vs. progestogens (norethisterone (NETA)) in combination with estrogen will be

  • 22 Oct, 2022
  • 1 location
The Therapeutic Effect of Medroxyprogesterone Acetate vs. LNG-IUS in Early-stage Endometrioid Carcinoma

In modern society, endometrial cancer (EC) and atypical hyperplasia is the most frequent desease which can affect the fertility of young patients. For young patients, there is a growing need to

  • 25 Oct, 2022
  • 1 location
A Study of RC48-ADC for the Treatment of HER2-expressing Gynecological Malignancies

This study will evaluate the effectiveness and safety of intravenous injection of RC48-ADC in the treatment of HER2 expression (HER2 positive and HER2 low expression) gynecological malignancies.

  • 21 Mar, 2022
  • 1 location
A Study for Assessing the Efficacy and Safety of BH4 in Radiation Enteritis

This present study envisaged a single-center, prospective, open-label, placebo and randomized controlled phase II clinical study to assess the efficacy and Safety of Tetrahydrobiopterin in Treating Radiation Enteritis in Gynecological Cancer Patients.

  • 13 Mar, 2022
  • 1 location
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers

The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic cancer that requires total pelvic exenteration Expected study-specific follow-up period per patient: 5 years according to standard follow-up …

  • 23 Mar, 2022