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Found 269 clinical trials
Featured trial
An Umbrella Study of INCMGA00012 Alone and in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-Based Chemotherapy (POD1UM-204) (POD1UM-204)

This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial cancer that has progressed on or after

metastatic endometrial cancer
cancer
platinum-based chemotherapy
  • 8 views
  • 20 Sep, 2022
  • 52 locations
Featured trial
A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of INCMGA00012 (formerly MGA012) in Patients with Advanced Solid Tumors

500 mg every 4 weeks in patients with endometrial cancer, specifically either microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR). Additionally, every 3 week (Q3W) flat-dosing

measurable disease
cancer
endometrial carcinoma
primary cancer
  • 295 views
  • 10 May, 2022
  • 17 locations
DOvEEgene Phase III Diagnostic Trial (DOvEEgeneIII)

associated with ovarian and endometrial cancer did diagnose these cancers earlier in the disease trajectory, with low-volume resectable disease, but only after the cancer had already become Stage III. So the

Accepts healthy volunteers
  • 0 views
  • 19 Sep, 2022
  • 2 locations
MPA Versus Dydrogesterone for Management of Endometrial Hyperplasia Without Atypia

To compare the efficacy of Medroxyprogesterone Acetate with dydrogesterone in patients having endometrial hyperplasia (EH) without atypia.

  • 0 views
  • 20 Jun, 2022
  • 1 location
Rucaparib vs Placebo Maintenance Therapy in Metastatic and Recurrent Endometrial Cancer

This study seeks to determine the effectiveness of Rucaparib as maintenance therapy for metastatic and recurrent endometrial cancer, after 1-2 prior lines of therapy.

  • 0 views
  • 14 Jul, 2022
  • 1 location
Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial Carcinoma

To explore the treatment efficacy of megestrol acetate plus rosuvastatin in patients with early endometrial carcinoma (EEC) seeking for conservative treatment.

  • 0 views
  • 18 Sep, 2022
  • 1 location
Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer

The purpose of the study is to investigate the effects of metformin in addition to the conventional progestin therapy in the fertility-sparing treatment of early stage endometrial cancer.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2021
  • 1 location
Study of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial Cancer

This is an open-label, multi-center, multi-corhort Phase II study of Envafolimab alone or with Lenvatinib in patients with advanced endometrial cancer.The primary objective is to evaluate objective response rate of envafolimab alone or with lenvatinib.

  • 0 views
  • 10 Jul, 2022
  • 19 locations
Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

This research study is evaluating a drug called Avelumab alone and in combination with Talazoparib or Axitinib as a possible treatment for recurrent or metastatic endometrial cancer.

  • 165 views
  • 10 Jul, 2022
  • 4 locations