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Found 18 clinical trials
Complications of Laparoscopic Hysterectomy and Sentinel Lymph Node Biopsy for Endometrial Carcinoma

Endometrial adenocarcinoma is believed to be a more treatable malignancy. Poor prognosis is associated with age, grade and depth of myometrial invasion, lymph node status, tumor size, invasion

  • 0 views
  • 30 May, 2021
  • 1 location
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

to determine the better modality of radiochemotherapy in stage III endometrial adenocarcinoma.

platelet count
cancer
carcinoma
neutrophil count
hysterectomy
  • 0 views
  • 24 Jan, 2021
  • 1 location
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

cancer
oophorectomy
pelvic radiation
serous adenocarcinoma
hysterectomy
  • 71 views
  • 28 Jul, 2021
  • 182 locations
Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer

The purpose of this study is to determine the effectiveness of the combination of abemaciclib and fulvestrant in treating this type of cancer and to determine the types and severity of side effects caused by treatment with abemaciclib and fulvestrant.

antibiotics
cancer
platelet count
mucinous adenocarcinoma
transitional cell carcinoma
  • 17 views
  • 19 Jul, 2021
  • 8 locations
Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment

This study will compare the effects of treatment with nivolumab alone versus those of nivolumab plus the experimental drug BMS-986205. Adding BMS-986208 to nivolumab could shrink the cancer or prevent it from returning, but it could also cause side effects.

cancer
mucinous adenocarcinoma
transitional cell carcinoma
oophorectomy
chemotherapy regimen
  • 1 views
  • 26 Jan, 2021
  • 7 locations
Abemaciclib and Letrozole in Treating Patients With Endometrial Cancer

This early phase I trial studies how well abemaciclib and letrozole work in treating patients with endometrial cancer and determines whether there are changes in patients' cancer cell biomarkers (a genetic feature or specific protein) for cell growth before and after treatment. Antihormone therapy with aromatase inhibitors, such as letrozole, …

  • 2 views
  • 15 May, 2021
  • 2 locations
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients

adenocarcinoma
cancer
neutrophil count
carcinosarcoma
endometrial adenocarcinoma
  • 0 views
  • 22 Mar, 2021
  • 1 location
Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

-surgical patients with either complex atypical hyperplasia (CAH; n=15) or grade 1 endometrial adenocarcinoma (EC; n=15). Participants:Women, over the age of 18 years, with biopsy-proven CAH/EC who

adenocarcinoma
cancer
hyperplasia
levonorgestrel
progestin
  • 195 views
  • 24 Jan, 2021
  • 2 locations
Onapristone and Anastrozole in Refractory Estrogen and Progesterone Positive Endometrial Cancer

This phase II trial studies the effect of onapristone and anastrozole in treating patients with hormone receptor positive endometrial cancer that has not responded to previous treatment (refractory). Progesterone and estrogen are hormones that can cause the growth of endometrial cancer cells. Onapristone blocks the use of progesterone by the …

cancer
serous adenocarcinoma
metastasis
hysterectomy
adenocarcinoma
  • 0 views
  • 12 Jun, 2021
  • 2 locations
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

This phase III trial compares whether the addition of pembrolizumab to radiation therapy is more effective than radiation therapy alone in reducing the risk of cancer coming back (recurrence) in patients with newly diagnosed stage I-II endometrial cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

  • 1 views
  • 29 Jul, 2021
  • 130 locations