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Found 2632 clinical trials
A Study of TRPC5 Channel Inhibitor in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

This is a phase 2a study evaluating the safety and tolerability of multiple ascending doses of GFB-887 in patients with diabetic nephropathy (DN), focal segmental glomerulosclerosis (FSGS), and treatment-resistant minimal change disease (TR-MCD).

hemoglobin a1c
minimal change disease
focal segmental glomerulosclerosis
glomerular filtration rate
  • 07 Apr, 2022
  • 64 locations
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete spinal cord injury. The investigators hypothesize that LT+TRT treatment …

body mass index
incomplete spinal cord injury
locomotor training
spinal cord disorder
  • 12 Sep, 2021
  • 2 locations
A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

The purpose of this study is to evaluate the clinical activity of gemcitabine, nab-paclitaxel, capecitabine, cisplatin, and irinotecan (GAX-CI) in patients with metastatic pancreatic cancer.

measurable lesion
metastatic pancreatic adenocarcinoma
administration intravenous
  • 10 Mar, 2022
  • 1 location
Camrelizumab Combined With Endostar for First-line Treatment in Subjects With Advanced Squamous NSCLC

treatment with Camrelizumab and Endo in advanced lung squamous cell carcinoma

neutrophil count
cancer chemotherapy
adjuvant chemotherapy
measurable disease
  • 01 Mar, 2022
  • 1 location
Effect of the Different Concentrations of Oral Dextrose Solution Applying Together With Supportive Positions on Pain During the Heel-Stick Sampling in Premature Infants

Within the scope of the newborn screening (metabolic and endocrine diseases) tests (NSTs), this research aims to determine the effect of the different concentrations of oral dextrose solution

  • 14 Jun, 2022
  • 1 location
Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer

Niraparib is an oral, potent and highly selective PARP1/2 inhibitor. It can be used as a single drug in HRD positive ovarian cancer patients for multi-line therapy. Bevacizumab is a recombinant humanized monoclonal antibody that inhibits tumor angiogenesis and is also recommended for the treatment of recurrent ovarian cancer. Clinical …

monoclonal antibodies
cancer chemotherapy
peritoneal cancer
ovarian cancer
  • 26 Jan, 2021
  • 1 location
Study of Intraocular Concentrations (Aqueous Humor, Vitreous Humor) of Antibiotics After Local and/or Systemic Administration in Endophthalmitis (CINEBIOPHTA)

complication following any endo-ocular surgery. It can be acute, occurring within 6 weeks post-operatively or delayed as after poor healing, or on a glaucoma filtration bubble. Endophthalmitis after cataract

  • 09 Feb, 2022
  • 1 location
Efficacy of Prolonged GnRH Test in Male Adolescents With Postoperative HH

and other endocrine disorders caused by HH. After a single injection of GnRH, the patients with poor response of luteinizing hormone and follicle stimulating hormone need to take extended provocation

luteinizing hormone
secondary hypogonadism
klinefelter syndrome
  • 25 Mar, 2022
  • 1 location
Gallium-68 Labeled Pentixafor PET/CT in Adrenal Masses

functional endocrine disorders. CXCR4 expression has been reported to be upregulated in aldosterone-producing adenomas and cortisol-producing adenomas; however, its expression is almost negligible in non

  • 07 May, 2021
  • 1 location
Patient Satisfaction With the Management of a Stopped Pregnancy in the First Trimester

benefiting from surgical treatment by endo-uterine aspiration for the management of a pregnancy stopped during the first trimester at the Toulouse University Hospital

  • 30 Nov, 2021
  • 1 location