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Found 2637 clinical trials
Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy

The aim of this study is to evaluate the effects of subantimicrobial dose doxycycline (50 mg/d), administered for 12 weeks, on patients with mild Thyroid-Associated Ophthalmopathy (TAO).

  • 26 Nov, 2021
  • 1 location
Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy

This study will see if the use of near infrared autofluorescence (NIRAF) detection with a 'Parathyroid Eye (PTeye)' for identifying parathyroid glands (PGs) during total thyroidectomy (TTx) is better than surgeon's detection alone. It compares risk, benefits and outcomes in TTx patients where NIRAF detection with PTeye for parathyroid identification …

  • 26 Mar, 2022
  • 1 location
Different Initial Insulin Dose Regimens on Time to Achieve Glycemic Targets and Treatment Safety in SIIT

To compare the effects of different initial insulin dose regimens during the short-term insulin intensive treatment on time to glycemic goal, hypoglycemia prevalence, glycemic variability and other safety problems in newly diagnosed type 2 diabetes mellitus(T2DM) patients, in order to investigate the rational of formula based initiation regimen.

plasma glucose
blood glucose monitoring
body mass index
hypoglycemic agents
  • 26 Oct, 2021
  • 1 location
Safety and Feasibility of Novel Therapy for Duodenal Mucosal Regeneration for Type II Diabetes (REGENT-1-US)

This is a multi-center, open-label study to assess the feasibility and preliminary safety of the Endogenex Device for endoscopic duodenal mucosal regeneration in patients with type 2 Diabetes inadequately controlled on 2-3 non-insulin glucose-lowering medications.

  • 02 May, 2022
  • 2 locations
A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both (SURPASS-PEDS)

The purpose of this study is to learn more about the safety and efficacy of tirzepatide compared to placebo in children or teenagers with type 2 diabetes taking metformin, or basal insulin, or both. The overall study will last about 60 weeks with up to 14 clinic visits and 6 …

hemoglobin a1c
type 2 diabetes mellitus
  • 13 Jun, 2022
  • 10 locations
Closed-loop Insulin Delivery In Type 1 Diabetes Pregnancies (CIRCUIT) - Internal Pilot (CIRCUIT)

This internal pilot trial will assess the feasibility and safety of a randomized controlled trial using the Tandem t:slim X2 pump with Control IQ technology in pregnant women with T1D. If funding for a larger multi-centre trial is obtained, the effects of using the Tandem t:slim X2 pump with Control …

injection of insulin
  • 11 Mar, 2022
  • 2 locations
Integration of Health Coaching and Diabetes Education in Type 2 Diabetes Mellitus Management at Primary Health Care

Type 2 Diabetes Mellitus is a chronic disease with increasing incidence globally. It needs a comprehensive and continuous management approach that includes five pillars: education, nutritional management, physical activity, pharmacological treatment, and monitoring. To achieve good glycemic control, prevention of complications, and good quality of life as diabetes management goals, …

  • 02 May, 2022
  • 1 location
Evaluation of Ocoxin-Viusid® in Advanced Pancreatic Adenocarcinoma

The investigators hypothesized that with the administration of the nutritional supplement Ocoxin-Viusid is expected to improve the quality of life and enhance tolerance to chemotherapy in at least 70% of patients diagnosed with advanced pancreatic adenocarcinoma, treated at the "Hermanos Ameijeiras" Surgical Clinical Hospital. Phase II clinical trial, open, multicenter, …

nutritional supplement
white blood cell count
cancer chemotherapy
pancreatic adenocarcinoma
  • 24 Feb, 2022
  • 1 location
The Effect of Mechanical Ventilation on the Occurrence of Myocardial Ischemia: a Pilot Study (VENTMICS)

The goal of the proposed pilot study is to determine which method can detect myocardial ischemia at the predefined timepoints during endo-CABG. Additionally, the investigators want to examine

  • 22 Mar, 2022
  • 1 location
An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D

This is an open-label, multicenter, Phase 1 study evaluating the safety and tolerability of VCTX210A combination product in patients with T1D

treatment regimen
  • 19 Apr, 2022
  • 1 location