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Found 2631 clinical trials
Detect V / CHEVENDO (Chemo vs. Endo)

Chemo- versus endocrine therapy in combination with dual HER2-targeted therapy of Herceptin (trastuzumab) and Perjeta (pertuzumab) plus Kisqali (ribociclib) in patients with HER2 positive and hormone-receptor positive metastatic breast cancer.

endocrine therapy
trastuzumab
primary tumor
letrozole
HER2
  • 35 views
  • 24 Jan, 2022
  • 1 location
Endo-perio Lesion's Treatment With Using Diode Laser 940nm

presented in periodontal pockets and also in root canals. To increase efficiency of endo-perio treatment there is used diode laser wavelength 940nm. Laser disinfection is done in periodontal pockets and

  • 0 views
  • 26 Jan, 2021
  • 1 location
HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant (AGNOHSTIC)

To compare the costs and effects of HYALOBARRIER GEL ENDO versus no HYALOBARRIER GEL ENDO for increasing the chance of conception leading to live birth measured at 30 weeks after randomization

ovulation induction
hysteroscopy
intrauterine insemination
myoma
uterine adhesions
  • 20 views
  • 06 Feb, 2022
  • 1 location
PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism

This study is limited to conduct in China only. The primary objective is to assess the treatment effect of daily TransCon PTH on serum calcium (sCa) levels within the normal range and stopping from therapeutic doses of active vitamin D (calcitriol) or active vitamin D analogue (alfacalcidol) and calcium at …

  • 0 views
  • 04 Jun, 2022
  • 1 location
Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS) (DIMOXIS)

Androgen excess is the cardinal biochemical feature of polycystic ovary syndrome (PCOS). Serum testosterone correlates with insulin resistance in PCOS, however, there is an urgent need to improve our understanding of the association between androgens and the risk of type 2 diabetes. 11-oxygenated steroids are the predominant androgens in PCOS …

insulin resistance
diabetes
testosterone level
androgens
insulin
  • 0 views
  • 10 May, 2022
  • 1 location
Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.

The hypothesis of a link between depression and Hypothalamic-Pituitary Axis (HPA) dysfunction is now experienced. Since a first description in 1949 this link has made the HPA one of the most investigated hormonal axis in depression. Many studies have demonstrated quantitative variations of circulating cortisol in situation of depression including …

antidepressants
glucocorticoids
metyrapone
psychiatric disorder
psychosis
  • 0 views
  • 27 Feb, 2022
  • 2 locations
Sleep and Physical Activity Intervention for Increasing Physical Activity in Overweight or Obese and Sedentary African Americans

This trial studies how well sleep and physical activity interventions work in increasing the physical activity of overweight or obese and sedentary African Americans. Sleep and physical activity interventions may help to increase physical activity among overweight and obese African American adults who do not get enough exercise.

body mass index
  • 217 views
  • 24 Feb, 2022
  • 1 location
Cost-utility of Ambulatory Surgery in the Management of Endometrial Cancer(AMBU-ENDO) (AMBU-ENDO)

To date, cost-utility, safety, and feasibility of ambulatory surgery versus traditional pathway in the management of endometrial cancer have never been prospectively assessed. The investigators hypothesize that ambulatory surgery versus standard pathway in the management of endometrial cancer is both safe, feasible and may impact on patient health-related quality of …

  • 1 views
  • 23 Feb, 2022
  • 1 location
Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo)

Common complications of the Boston keratoprosthesis type 1 (KPro) surgery include retroprosthetic membrane formation, glaucoma, and retinal detachment. Often pars plana vitrectomy (PPV) is performed at the same time as KPro surgery for different indications. It has been shown to reduce postoperative complications in comparison to when it is performed …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Traumacel PULVIS and Traumacel ENDO Applicator in the Post-market Surveillance Phase

. The broadness of application allows for use in procedures performed in the standard way as well as endoscopically. Traumacel ENDO Applicator is a single use, flexible, manual apparatus designed

  • 0 views
  • 17 Jun, 2022
  • 1 location