Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 54 clinical trials
Study of Regional Cerebral Oxygenation and Brain Blood Volume Changes During Carotid Endarterectomy Using the NeurOS System

Study of Regional cerebral Oxygenation and Brain Blood Volume changes during Carotid Endarterectomy using the NeurOS system

  • 0 views
  • 18 Feb, 2021
  • 1 location
Effect of Short Term Atorvastatin Treatment 80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions

Atherosclerosis is a disease in which the blood vessels become blocked by plaques (consisting of fat, calcification, and fibrous tissue), reducing blood flow to vital organs and tissues.Blockage of the carotid arteries in the neck is a major cause of stroke. One way of treating carotid atherosclerosis is with cholesterol-lowering …

coronary disease
atorvastatin
heart disease
atherosclerosis
carotid atherosclerosis
  • 24 views
  • 07 Nov, 2020
  • 1 location
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …

cerebral infarction
acute stroke
stenosis
ischemia
stroke
  • 12 views
  • 22 Jan, 2021
  • 1 location
Statin Neuroprotection and Carotid Endarterectomy: Safety Feasibility and Outcomes

The investigators hypothesize that pre-operative statin use is neuroprotective at maximal doses. The goals are to determine the safety, feasibility, and efficacy of maximizing statin doses for two weeks (12-18 days) prior to CEA using change in performance on a battery neuropsychometric tests as outcome measure. Study will recruit patients …

cerebral infarction
statin
atorvastatin
neurological symptoms
arterial stenosis
  • 14 views
  • 21 Jan, 2021
  • 6 locations
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

brain infarctions by the activation of endogenous fibrinolytic system during carotid endarterectomy (CEA) in patients with 70% symptomatic or asymptomatic internal carotid artery stenosis. The

ischemic attack
MRI
stenosis
endarterectomy
carotid artery stenosis
  • 6 views
  • 26 Jan, 2021
  • 2 locations
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will

ischemic attack
stenosis
transient ischemic attack
endarterectomy
carotid revascularization
  • 1024 views
  • 02 Jun, 2021
  • 148 locations
Transfusion Trigger After Operations in High Cardiac Risk Patients

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

vascular surgical procedures
angina pectoris
percutaneous coronary intervention
cancer
exercise stress test
  • 12 views
  • 16 May, 2021
  • 16 locations
Assessment of Cognitive Function in Patients Undergoing Elective Carotid Endarterectomy

Assessment of cognitive function in patients undergoing elective carotid endarterectomy Classical treatment for ICA stenosis is carotid endarterectomy (CEA), which has been proven

carotid endarterectomy
cognitive decline
mental deterioration
mini-mental state examination
stroke
  • 0 views
  • 25 Jan, 2021
  • 1 location
Comparison of the Effects of Phenylephrine and Norepinephrine on Cardiac Function During Carotid Artery Surgery

This will be a prospective, randomized, double-blinded, cross-over clinical trial to compare the effects of phenylephrine or norepinephrine on cardiac function during carotid artery surgery in patients under general anesthesia. The effect of the vasopressor on cardiac function will be measured using electrocardiography, transesophageal echocardiography and cardiac troponin I intraoperatively …

  • 9 views
  • 07 Nov, 2020
  • 1 location
A Study of Evolocumab on Carotid Artery Atherosclerotic Plaque Morphology Prior to Carotid EndArterectomy

atherosclerotic plaques in higher risk subjects with severe asymptomatic but vulnerable plaques undergoing carotid endarterectomy.

total cholesterol
low-density lipoprotein
stenosis
carotid artery stenosis
diabetes
  • 0 views
  • 26 Jan, 2021
  • 1 location