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Found 52 clinical trials
Study of Regional Cerebral Oxygenation and Brain Blood Volume Changes During Carotid Endarterectomy Using the NeurOS System

Study of Regional cerebral Oxygenation and Brain Blood Volume changes during Carotid Endarterectomy using the NeurOS system

  • 0 views
  • 18 Feb, 2021
  • 1 location
Effect of Short Term Atorvastatin Treatment 80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions

Atherosclerosis is a disease in which the blood vessels become blocked by plaques (consisting of fat, calcification, and fibrous tissue), reducing blood flow to vital organs and tissues.Blockage of the carotid arteries in the neck is a major cause of stroke. One way of treating carotid atherosclerosis is with cholesterol-lowering …

atherosclerosis
hmg-coa reductase inhibitor
stroke
coronary disease
endarterectomy
  • 24 views
  • 07 Nov, 2020
  • 1 location
External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis

Intracranial stenosis is prevalent among Asians and constitute a common cause of cerebral ischemia. While the best medical therapy carries stroke recurrence rates in access of 10% per year, intracranial stenting was associated with unacceptable peri-procedural ischemic events. Cerebral ischemic events are strongly related to the severity of intracranial stenosis, …

stroke
acute stroke
ischemia
stenosis
cerebral infarction
  • 12 views
  • 22 Jan, 2021
  • 1 location
SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

brain infarctions by the activation of endogenous fibrinolytic system during carotid endarterectomy (CEA) in patients with 70% symptomatic or asymptomatic internal carotid artery stenosis. The

carotid artery stenosis
stroke
endarterectomy
MRI
angiography
  • 6 views
  • 26 Jan, 2021
  • 2 locations
Statin Neuroprotection and Carotid Endarterectomy: Safety Feasibility and Outcomes

The investigators hypothesize that pre-operative statin use is neuroprotective at maximal doses. The goals are to determine the safety, feasibility, and efficacy of maximizing statin doses for two weeks (12-18 days) prior to CEA using change in performance on a battery neuropsychometric tests as outcome measure. Study will recruit patients …

neurological symptoms
ischemia
arterial stenosis
stroke
endarterectomy
  • 14 views
  • 21 Jan, 2021
  • 6 locations
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will

carotid revascularization
endarterectomy
transient ischemic attack
stroke
angiography
  • 1024 views
  • 03 May, 2021
  • 145 locations
Transfusion Trigger After Operations in High Cardiac Risk Patients

The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is associated with decreased risk of adverse postoperative outcomes compared to a restrictive transfusion …

bypass surgery
cancer
vascular surgical procedures
ischemia
stroke
  • 12 views
  • 26 Jan, 2021
  • 14 locations
Assessment of Cognitive Function in Patients Undergoing Elective Carotid Endarterectomy

Assessment of cognitive function in patients undergoing elective carotid endarterectomy Classical treatment for ICA stenosis is carotid endarterectomy (CEA), which has been proven

stroke
cognitive decline
mental deterioration
carotid endarterectomy
mini-mental state examination
  • 0 views
  • 25 Jan, 2021
  • 1 location
Imaging of Unstable Carotid Plaque in Patient Referred to Endarterectomy

This study will assess unstable plaque imaging features by using high resolution MR imaging and Sodium Fluoride F-18 PET. This is a comparative study between symptomatic and asymptomatic patient referred to carotid endateriectomy, with reference to pathologic analysis of plaque components

fluoride
endarterectomy
stenosis
stroke
  • 2 views
  • 23 Jan, 2021
  • 1 location
Comparison of the Effects of Phenylephrine and Norepinephrine on Cardiac Function During Carotid Artery Surgery

This will be a prospective, randomized, double-blinded, cross-over clinical trial to compare the effects of phenylephrine or norepinephrine on cardiac function during carotid artery surgery in patients under general anesthesia. The effect of the vasopressor on cardiac function will be measured using electrocardiography, transesophageal echocardiography and cardiac troponin I intraoperatively …

  • 9 views
  • 07 Nov, 2020
  • 1 location